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Table 1 Six prognostic indexes for patients with non-small cell lung cancer with brain metastases

From: Survival time following resection of intracranial metastases from NSCLC-development and validation of a novel nomogram

Prognostic factors RPA SIR BS-BM GGS DS-GPA NSCLC-RADES
Sample 1200 65 110 479 5067 514
Age(years) <65/≥65 ≤50(2′), 51–59(1′), ≥60(0′) _ ≥65(1′), <65(0′) <50(1′), 50–60(0.5′), >60(0′)  
gender       M (2′), F (5′)
KPS (%) ≥70/<70 80–100(2′), 60–70(1′), ≤50(0′) 80–100(1′), ≤70(0′) <70(1′), ≥70(0′) 90–100(1′), 70–80(0.5′), <70(0′) <70(1′), ≥70(5′)
CPT Y/N   Y (1′), N (0′)    
ECM Y/N CR (2′), PR/stable (1′), PD (0′) N (1′), Y (0′) Y (1′), N (0′) N (1′), Y (0′) Y (2′), N (5′)
Vol. of BM(cm3) _ <5(2′), 5–13(1′), >13(0′) _ _ _ _
Number of BM _ 1(2′), 2(1′), ≥3(0′) _ _ 1(1′), 2–3(0.5′), >3(0′) _
Class I All 4 favorable factors 8–10’ 3’ 0’ 0–1’ 5–9’
Class II others 4–7’ 2’ 1’ 1.5–2’ 11–12’
Class III KPS < 70 1–3’ 1’ 2’ 2.5–3’ 15’
Class IV    0’ 3’ 3.5–4’  
  1. RPA recursive partitioning analysis, SIR Score Index for Radiosurgery, BS-BM basic score for BM, GGS Golden Grading System, DS-GPA disease-specific graded prognostic assessment, CPT control of primary tumor, ECM extracranial metastases, BM brain metastases, Y yes, N no, M male, F female, KPS Karnofsky performance status, CR complete response, PR partial response, PD progressive disease