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Table 1 Six prognostic indexes for patients with non-small cell lung cancer with brain metastases

From: Survival time following resection of intracranial metastases from NSCLC-development and validation of a novel nomogram

Prognostic factors

RPA

SIR

BS-BM

GGS

DS-GPA

NSCLC-RADES

Sample

1200

65

110

479

5067

514

Age(years)

<65/≥65

≤50(2′), 51–59(1′), ≥60(0′)

_

≥65(1′), <65(0′)

<50(1′), 50–60(0.5′), >60(0′)

 

gender

     

M (2′), F (5′)

KPS (%)

≥70/<70

80–100(2′), 60–70(1′), ≤50(0′)

80–100(1′), ≤70(0′)

<70(1′), ≥70(0′)

90–100(1′), 70–80(0.5′), <70(0′)

<70(1′), ≥70(5′)

CPT

Y/N

 

Y (1′), N (0′)

   

ECM

Y/N

CR (2′), PR/stable (1′), PD (0′)

N (1′), Y (0′)

Y (1′), N (0′)

N (1′), Y (0′)

Y (2′), N (5′)

Vol. of BM(cm3)

_

<5(2′), 5–13(1′), >13(0′)

_

_

_

_

Number of BM

_

1(2′), 2(1′), ≥3(0′)

_

_

1(1′), 2–3(0.5′), >3(0′)

_

Class I

All 4 favorable factors

8–10’

3’

0’

0–1’

5–9’

Class II

others

4–7’

2’

1’

1.5–2’

11–12’

Class III

KPS < 70

1–3’

1’

2’

2.5–3’

15’

Class IV

  

0’

3’

3.5–4’

 
  1. RPA recursive partitioning analysis, SIR Score Index for Radiosurgery, BS-BM basic score for BM, GGS Golden Grading System, DS-GPA disease-specific graded prognostic assessment, CPT control of primary tumor, ECM extracranial metastases, BM brain metastases, Y yes, N no, M male, F female, KPS Karnofsky performance status, CR complete response, PR partial response, PD progressive disease