Table 4 The distribution of combinations of Arg399Gln of gene XRCC1 and T309G of gene MDM2 polymorphic markers in Kyrgyz women with BC and controls
XRCC1/MDM2 genotypes | Cases, n (%) | Controls, n (%) | OR (95% CI) | χ2/р |
|---|---|---|---|---|
Arg399Arg/G309G | 12 (10) | 17 (17) | Reference | |
Arg399Arg/T309G | 18 (15) | 31 (30) | 0.82 (0.32–2.11) | 0.17/0.684 |
Arg399Arg/T309T | 8 (7) | 8 (8) | 1.42 (0.42–4.84) | 0.31/0.578 |
Arg399Gln/ G309G | 14 (12) | 8 (8) | 2.48 (0.79–7.76) | 2.48/0.115 |
Arg399Gln/ T309G | 38 (32) | 18 (18) | 3.00 (1.18–7.56) | 4.49/0.034 |
Arg399Gln/ T309T | 16 (14) | 8 (8) | 2.83 (0.92–8.73) | 3.37/0.066 |
Gln399Gln/ G309G | 3 (3) | 3 (3) | 1.42 (0.24–8.26) | 0.15/0.697 |
Gln399Gln/ T309G | 6 (5) | 6 (5) | 1.42 (0.37–5.48) | 0.26/0.613 |
Gln399Gln/ T309T | 2 (2) | 3 (3) | 1.42 (0.17–11.51) | 0.11/0.74 |