Fig. 4

Knockdown of SR-BI attenuated migration (a) and invasion (b) of ccRCC cells. Wound closure assays showed that 786-O (c, e) and Caki-1 (d, f) cells transfected with si-SR-BI healed the gaps much slower than control cells at the indicated time points. *P < 0.05, **P < 0.01, ***P < 0.001