Table 2 Comparison of sensitivity as well as accuracy, specificity, PPV,NPV of preoperative T staging for lower rectal cancer using CTC with MPR and MRI
CTC with MPR (N=45) | MRI (n=34) | ||||||||||||
ctT1 | ctT2 | ctT3 | ctT4 | n | sensitivity | mrT1 | mrT2 | mrT3 | mrT4 | n | sensitivity | ||
pT1 | 5 | 1 | 6 | 83% | pT1 | 0 | 1 | 1 | 2 | 0% | |||
pT2 | 2 | 14 | 1 | 17 | 82% | pT2 | 8 | 7 | 15 | 53% | |||
pT3 | 21 | 21 | 100% | pT3 | 1 | 15 | 16 | 94% | |||||
pT4 | 1 | 1 | 100% | pT4 | 1 | 1 | 100% | ||||||
7 | 14 | 23 | 1 | 45 | 91% | 0 | 10 | 23 | 1 | 34 | 71% | ||
pT1 | pT2 | pT3 | |||||||||||
CTC (n=6) | MRI (n=2) | CTC (n=17) | MRI (n=15) | CTC (n=21) | MRI (n=16) | ||||||||
Accuracy | 93% (42/45) | 94% (32/34) | 93% (42/45) | 74% (25/34) | 96% (43/45) | 74% (25/34) | |||||||
Sensitivity | 83% (5/6) | 0% (0/2) | 82% (14/17) | 53% (8/15) | 100% (21/21) | 94% (15/16) | |||||||
Specificity | 95% (37/39) | 100% (32/32) | 100% (28/28) | 89% (17/19) | 92% (22/24) | 56% (10/18) | |||||||
PPV | 71% (5/7) | - (0/0) | 100% (14/14) | 80% (8/10) | 91% (21/23) | 65% (15/23) | |||||||
NPV | 97% (37/38) | 94% (32/34) | 90% (28/31) | 71% (17/24) | 100% (22/22) | 91% (10/11) | |||||||