Fig. 3

miR-486-5p promotes cervical cancer cell proliferation in vitro. a Cell proliferation assay comparing HeLa cells transfected with miR-486-5p inhibitor sponge (red) or control miRNA (black) for 96 h. b Cell proliferation assay comparing SiHa cells transfected with miR-486-5p mimic (blue) or control miRNA (black) for 96 h. c-d Colony formation assay: HeLa cells transfected with miR-486-5p inhibitor sponge (Inhibitor) or control miRNA (Mock) were incubated in 6-well culture plates. Colonies were counted after 15 days. e-f Colony formation assay: SiHa cells transfected with miR-486-5p mimic (Mimic) or control miRNA (Mock) were cultured in 6-well culture plates. Colonies were counted after 15 days. *P < 0.05, ** P < 0.01, *** P < 0.001, compared with Mock