Table 3 Univariate and multivariate survival analyses of OS and CSS in patients with colorectal cancer

Age (y)

 ≥60

1

1

1

 <60

0.777 (0.632–0.955)

0.737 (0.597–0.910)

0.873 (0.702–1.086)

Gender

 Male

1

1

1

 Female

0.766 (0.624–0.940)

0.730 (0.591–0.902)

0.825 (0.663–1.026)

Tumor Size (cm)

 ≥4.6

1

1

 <4.6

0.917 (0.751–1.120)

0.904 (0.729–1.120)

Tumor location

 Colon

1

1

 Rectum

1.036 (0.846–1.268)

1.017 (0.819–1.264)

Differentiation

 Well - moderate

1

1

1

1

 Poor - undifferentiated

2.438 (1.836–3.237)

1.647 (1.233–2.198)

2.621 (1.950–3.524)

1.644 (1.216–2.221)

pT category

 T1

1

1

1

1

 T2

1.596 (0.486–5.239)

1.390 (0.423–4.573)

0.996 (0.293–3.382)

0.825 (0.243–2.808)

 T3

4.362 (1.393–13.665)

2.132 (0.677–6.715)

3.725 (1.187–11.691)

1.689 (0.534–5.338)

 T4

6.353 (2.029–19.890)

2.910 (0.924–9.165)

5.670 (1.809–17.765)

2.416 (0.766–7.627)

pN category

 pN0

1

1

1

1

 pN1

4.779 (3.702–6.170)

4.132 (3.189–5.354)

5.678 (4.249–7.587)

4.856 (3.622–6.512)

 pN2

11.353 (8.583–15.016)

10.215 (7.648–13.643)

14.388 (10.556–19.610)

11.760 (8.565–16.147)

Distant metastasis

 Negative

1

1

1

1

 Positive

3.690 (2.349–5.797)

2.226 (1.407–3.524)

3.974 (2.497–6.324)

2.200 (1.375–3.522)

TNM stage

 I

1

1

 II

2.398 (1.327–4.332)

4.854 (1.944–12.118)

 III

12.092 (6.931–21.097)

27.933 (11.524–67.709)

 IV

20.970 (10.408–42.248)

50.019 (18.648–134.163)

LMR

 ≥5.8

1

1

1

1

 <5.8

1.565 (1.239–1.976)

1.054 (0.809–1.373)

1.541 (1.201–1.977)

1.064 (0.804–1.409)

NLR

 ≥2.0

1

1

1

1

 <2.0

0.621 (0.508–0.760)

0.758 (0.598–0.960)

0.620 (0.499–0.770)

0.738 (0.573–0.950)

PLR

 ≥134.6

1

1

1

1

 <134.6

0.710 (0.582–0.867)

0.873 (0.697–1.094)

0.652 (0.526–0.807)

0.841 (0.661–1.070)

PNI

 ≥46.4

1

1

1

1

 <46.4

1.503 (1.199–1.884)

1.238 (0.972–1.576)

1.552 (1.220–1.975)

1.272 (0.985–1.643)