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Table 3 Validation of selected targets for microRNAs deregulated in metastatic canine mammary cancer

From: MicroRNA expression patterns in canine mammary cancer show significant differences between metastatic and non-metastatic tumours

Gene Mean difference Lower Upper p-value
CDC6 1.662166667 0.296219571 3.028113763 0.014739925
CCNE1 1.805333334 0.698148282 2.912518385 0.00111525
MYBL2 1.469333333 0.095498643 2.843168024 0.034267
PDCD10 0.315 −1.466393723 2.096393723 0.899858502
ERBB2IP 1.863333333 0.181873946 3.544792721 0.027609459
SON 1.691333333 0.149694553 3.232972114 0.029382504
STK4 2.356333333 0.708656745 4.004009921 0.004014445
CDC27 2.316333334 0.684213855 3.948452812 0.004297527
PRC1 3.368333333 1.644772232 5.091894434 0.000132898
CDC37 3.250833333 1.273918023 5.227748644 0.001019454
TTK 2.8475 0.856445769 4.838554231 0.004013127
SKIL 2.291666667 0.327926258 4.255407076 0.019726893
BUB3 0.976666667 −0.467839044 2.421172377 0.232448632
SPIN1 1.248333333 −0.448209573 2.944876239 0.180817071
  1. The analysis performed on ten malignant non-metastatic tumours and ten malignant metastatic tumours. Statistical analysis was made on Ct values normalized with a housekeeping gene; one-way ANOVA followed by Tukey’s HSD post hoc tests