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Table 2 Validation of microarray results in tumour samples

From: MicroRNA expression patterns in canine mammary cancer show significant differences between metastatic and non-metastatic tumours

microRNA microarray p-value RT-qPCR p-value Average RT-qPCR repeats, normalized
Control Benign Malignant non-metastatic Malignant metastatic
let-7c < 1e-07 0.02892256 2.066592593 1.551592593 0.885092593 0
miR-26b < 1e-07 0.00001507 1.56060648 0.04060648 −0.57989352 −1.02131944
miR-26a < 1e-07 0.00003571 1.11365741 0.50621296 −0.58834259 −1.03152778
miR-30a 3.00E-07 0.00367713 −0.09936889 0.71563112 0.08413112 −0.70039334
miR-148a 3.00E-07 0.04282469 0.32479167 0.55945833 −0.50670833 −0.37754167
miR-29c 5.00E-07 0.00019157 0.79212037 0.30412037 −0.25387963 −0.84236111
miR-30c 2.70E-06 0.00133947 0.2615463 0.59621296 0.0315463 −0.88930556
miR-299 5.40E-06 0.04632324 1.899074074 0.425074074 2.399074074 0
miR-10b 6.00E-06 0.01635353 0.9961408 0.07058524 −0.46735921 −0.59936683
miR-30b 1.74E-05 0.00557426 0.61328913 0.43528913 −0.40171087 −0.6468674
  1. one-way ANOVA p-values for microarray results and RT-qPCR results; RT-qPCRs performed for 10 microRNAs on 47 samples (5 controls, 5 benign tumours, 10 malignant non-metastatic tumours and 27 malignant metastatic tumours)