Fig. 9

Heat map − selected targets for microRNAs deregulated in metastatic canine mammary cancer. The scaled expression of CDC6, CCNE1, MYBL2, PDCD10, ERBB2IP, SON, STK4, CDC27, PRC1, CDC37, TTK, SKIL, BUB3 and SPIN1. The analysis performed on ten malignant non-metastatic tumours and ten malignant metastatic tumours. Statistical analysis was made on Ct values normalized with a housekeeping gene; one-way ANOVA followed by Tukey’s HSD post hoc tests. Legend: log2 FC – log base 2 from fold change, * – p value <0.05, ** – p value <0.01, *** – p value <0.001