Table 4 Cox regression multivariate analyses of factors associated with early mortality and early recurrence in hepatocellular carcinoma after hepatectomy

  class II/III vs. class I

2.847 (1.884~4.302)

 ALBI score^b

  grade 2 vs. grade 1

2.309 (1.577~3.383)

  grade 3 vs. grade 1

N/A^k

 MELD score^c

  grade 2 vs. grade 1

1.218 (0.782~1.897)

  grade 3 vs. grade 1

1.873 (0.830~4.231)

 Alcohol consumption (Yes)

1.799 (1.105~2.930)

 Cigarette smoking (Yes)

1.110 (0.710~1.734)

 Age > 80 (year-old)

1.988 (0.907~4.354)

 Pre-OP symptoms^d (Yes)

1.411 (0.956~2.083)

 Pre-OP treatment^e (Yes)

1.271 (0.765~2.111)

 Pre-OP platelets < 100 (1000/uL)

1.453 (0.905~2.332)

 Pre-OP total bilirubin > 2.0 (mg/dL)

1.377 (0.469~4.039)

 Pre-OP hemoglobin < 10 (g/dL)

1.102 (0.596~2.038)

 ICG-15^f > 10 (%)

1.081 (0.740~1.580)

 OP duration^g > 270 (mins)

1.295 (0.875~1.915)

 Tumor size > 10 (cm)

1.770 (1.130~2.771)

  class II/III vs. class I

1.640 (1.352~1.988)

 ALBI score^b

  grade 2 vs. grade 1

1.382 (1.190~1.606)

  grade 3 vs. grade 1

0.962 (0.301~3.077)

 MELD score^c

  grade 2 vs. grade 1

0.952 (0.787~1.150)

  grade 3 vs. grade 1

1.015 (0.683~1.509)

 Alcohol consumption (Yes)

1.249 (1.003~1.557)

 Cigarette smoking (Yes)

1.258 (1.057~1.498)

 Pre-OP symptoms^d (Yes)

1.006 (0.855~1.184)

 Pre-OP treatment^e (Yes)

1.183 (0.953~1.469)

 Pre-OP total bilirubin > 2.0 (mg/dL)

1.513 (0.921~2.487)

 Pre-OP hemoglobin < 10 (g/dL)

1.215 (0.903~1.634)

 Pre-OP ALT^h > 40 (U/L)

1.077 (0.940~1.234)

 ICG-15^f > 10%

1.347 (1.167~1.554)

 Tumor size > 10 (cm)

1.773 (1.456~2.160)

 Inflow controlⁱ (Yes)

1.162 (0.985~1.370)