Table 1 Summary of splicing changes identified in RON transcripts of lung cancer cell lines
Skipping of Exon(s) | Loss of nucleotides (from – to) | Nucleotides lost (n) | Frameshift | Premature stop codon | Amino acids lost (n) | Freq. of occurrence (n/23) |
|---|---|---|---|---|---|---|
2 | 1231–1419 | 189 | No | No | 63 | 1 |
2–3 | 1231–1548 | 318 | No | No | 106 | 4 |
5–6 | 1720–2046 | 327 | No | No | 109 | 1 |
6 | 1881–2046 | 166 | Yes | Yes | 6 | |
8–9 | 2184–2439 | 256 | Yes | Yes | 13 |