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Table 3 Cox regression analysis for the prediction of cancer-specific survival in patients with urothelial bladder cancer (n = 88, number of events = 20)

From: YRNA expression predicts survival in bladder cancer patients

 

Univariate analysis

Multivariate analysisa

p-value

HR

95% CI

p-value

HR

95% CI

RNY1, low vs high

0.005

3.57

1.46–8.72

0.676

1.22

0.47–3.17

RNY3, low vs high

0.012

3.29

1.29–8.35

0.715

1.20

0.45–3.25

RNY4, low vs high

0.062

2.34

0.96–5.69

0.816

0.90

0.35–2.27

RNY5, low vs high

0.593

0.79

0.32–1.90

0.494

0.73

0.30–1.80

MIBC vs. NMIBC

6.7e-04

12.89

2.95–56.26

0.017

7.97*

1.45–43.71

pN-stage, pN1 vs pN0

0.001

4.38

1.81–10.59

0.741

1.19*

0.43–3.29

cM-stage, M1 (n = 2) vs M0

2.9e-04

21.2

4.06–110.8

x

x

x

Grade, G3 vs G1 + G2

0.006

4.72

1.57–14.21

0.347

1.82*

0.52–6.35

  1. Comments: aIn case of every YRNA data is shown for separate multivariate model with “MIBC vs NMIBC”, pN-Stage and Grade as co-variates; *HR, p-value, 95% CI shown for multivariate model with RNY1. Other YRNAs (RNY3, RNY4, RNY5) showed similar results
  2. Analysis for YRNAs is based on the best cut-off, the same as in Kaplan-Meier/log-rank analysis: RNY1–0.082, RNY3–0.175, RNY4–0.338, RNY5–1.151. Abbreviations: MIBC muscle-invasive bladder cancer, NMIBC non-muscle-invasive bladder cancer
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BMC Cancer

ISSN: 1471-2407

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