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Table 2 Relative YRNA expression levels in the tumor and normal urothelial tissue and discriminative capabilities of the YRNAs to predict the tissue dignity (tumor vs. normal)

From: YRNA expression predicts survival in bladder cancer patients

 

Expression median (range)

ROC analysis

Sensitivity

Specificity

Cut-off

BCA (n = 88)

CTRL (n = 30)

AUC

95%CI

   

RNY1

0.15 (0.0–1.75)

0.59 (0.02–2.54)

0.851

0.760–0.941

73.3%

90.9%

0.471

RNY3

0.21 (0.0–1.96)

0.84 (0.03–3.24)

0.863

0.778–0.949

80.0%

88.6%

0.527

RNY4

0.61 (0.0–8.96)

2.92 (0.05–18.41)

0.844

0.755–0.933

86.7%

75.0%

1.061

RNY5

1.15 (0.0–8.41)

2.34 (0.07–18.75)

0.715

0.601–0.829

73.3%

75.0%

1.948

  1. Comments: BCA – tissue samples with urothelial cancer (bladder cancer); CTRL – control samples (normal urothelial tissue); AUC, area under the curve; 95%CI, 95% confidence interval