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Table 2 Relative YRNA expression levels in the tumor and normal urothelial tissue and discriminative capabilities of the YRNAs to predict the tissue dignity (tumor vs. normal)

From: YRNA expression predicts survival in bladder cancer patients

  Expression median (range) ROC analysis Sensitivity Specificity Cut-off
BCA (n = 88) CTRL (n = 30) AUC 95%CI    
RNY1 0.15 (0.0–1.75) 0.59 (0.02–2.54) 0.851 0.760–0.941 73.3% 90.9% 0.471
RNY3 0.21 (0.0–1.96) 0.84 (0.03–3.24) 0.863 0.778–0.949 80.0% 88.6% 0.527
RNY4 0.61 (0.0–8.96) 2.92 (0.05–18.41) 0.844 0.755–0.933 86.7% 75.0% 1.061
RNY5 1.15 (0.0–8.41) 2.34 (0.07–18.75) 0.715 0.601–0.829 73.3% 75.0% 1.948
  1. Comments: BCA – tissue samples with urothelial cancer (bladder cancer); CTRL – control samples (normal urothelial tissue); AUC, area under the curve; 95%CI, 95% confidence interval