Table 3 GRADE profile evidence of the included studies
Outcome indicator | No. of studies | Quality assessment | No. of patients | Effect | Quality | Importance | ||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
Risk of bias | Inconsistency | Indirectness | Imprecision | publication bias | LAP | OPEN | Relative (95% CI) | Absolute | ||||
Operation time | 5 | no serious risk of bias | very seriousa | no serious indirectness | seriousb | None | 90 | 86 | WMD −0.87 (−47.50~47.75) | ⊕⊝⊝⊝ very low | IMPORTANT | |
Blood loss | 5 | no serious risk of bias | serious | no serious indirectnessa | seriousb | None | 89 | 108 | WMD −34.38 (−79.60~10.84) | ⊕⊝⊝⊝ very low | IMPORTANT | |
Postoperative complications | 6 | no serious risk of bias | no serious inconsistency | no serious indirectness | seriousa | Maybed | 185 | 194 | RR 0.65 (0.38~1.12)c | ⊕ ⊕ ⊝⊝ low | CRITICAL | |
Postoperative hospital stay | 6 | no serious risk of bias | very seriousa | no serious indirectness | seriousb | None | 113 | 122 | WMD −2.01 (−3.83~ − 0.18) | ⊕⊝⊝⊝ very low | IMPORTANT | |
Overall recurrence rate | 7 | no serious risk of bias | no serious inconsistency | no serious indirectness | seriousa | None | 203 | 214 | RR 0.56 (0.29~1.06)c | ⊕ ⊕ ⊕⊝ moderate | CRITICAL | |
Disease-free survival | 5 | no serious risk of bias | no serious inconsistency | no serious indirectness | no serious imprecision | None | 162 | 171 | HR 0.40 (0.17~0.91) | ⊕ ⊕ ⊕⊝ moderate | CRITICAL | |
Overall survival | 4 | no serious risk of bias | no serious inconsistency | no serious indirectness | serious | None | 149 | 158 | HR 0.11 (0.03~0.43) | ⊕ ⊕ ⊕⊝ moderate | CRITICAL | |