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Table 3 Associations between HSV types 1 or 2 and cancer status-NHANES 1999–2014

From: Seropositivity to herpes simplex virus type 2, but not type 1 is associated with cervical cancer: NHANES (1999–2014)

HSV1

aOR

(95% CI)

P value

Any cancer

1.32

(0.97–1.79)

0.07

Breast cancer

2.04

(0.78–5.37)

0.14

Cervical cancer

1.04

(0.60–1.80)

0.89

Ovarian cancer

1.57

(0.37–6.64)

0.54

Uterine cancer

6.03

(1.52–23.87)

0.01

HSV2

aOR

(95% CI)

P value

Any cancer

1.47

(1.01–2.14)

0.04

Breast cancer

0.69

(0.20–2.40)

0.56

Cervical cancer

1.72

(1.06–2.79)

0.03

Ovarian cancer

1.56

(0.50–4.94)

0.44

Uterine cancer

3.49

(1.03–11.85)

0.04

  1. Abbreviations: HSV1, herpes simplex virus type 1; HSV2, herpes simplex virus type 2; aOR, Adjusted odds ratio; CI, confidence interval; NHANES, National Health and Nutrition Examination Survey
  2. Model was adjusted for age, education, race, poverty income ratio, body mass index, smoking status, alcohol-use status and HIV status