Feasibility of structured endurance training and Mediterranean diet in BRCA1 and BRCA2 mutation carriers – an interventional randomized controlled multicenter trial (LIBRE-1)

Table 3 Adherence to the lifestyle intervention program within the first 3 months and baseline characteristics (n = 26)

	Adherence positive (≥ 70% participation in the intervention sessions)	Adherence negative (< 70% participation in the intervention sessions)	P-value
Nutrition courses	21/26 (81%)	5/26 (19%)
Cancer, n	16	2	0.610
Age*, years	43 (29–72)	41 (28–49)	0.686
BMI*, kg/m²	23 (18–45)	24 (20–37)	0.610
VO₂peak*, ml/kg/min	24 (12–42)	23 (16–41)	0.952
O₂ at VT1*, ml/kg/min	14 (8–28)	14 (10–21)	0.343
IPAQ, MET*min/wk	5130 (347–14,166)	6167 (4583–7812)	0.629
Training courses	21/26 (81%)	5/26 (19%)
Cancer, n	14	4	0.114
Age*, years	42 (28–72)	41 (36–51)	0.286
BMI*, kg/m²	23 (18–45)	24 (20–37)	0.857
VO₂peak*, ml/kg/min	24 (12–42)	22 (16–37)	0.467
O₂ at VT1*, ml/kg/min	14 (8–28)	15 (10–21)	1.000
IPAQ, MET*min/wk	5376 (347–14,166)	5375 (2826–7812)	0.970
Nutrition and training	19/26 (73%)	7/26 (27%)
Cancer, n	14	4	0.534
Age*, years	43 (29–27)	41 (28–51)	0.821
BMI*, kg/m²	23 (18–45)	24 (20–37)	0.778
VO₂peak*, ml/kg/min	24 (12–42)	23 (16–41)	0.955
O₂ at VT1*, ml/kg/min	14 (8–28)	15 (10–21)	0.642
IPAQ, MET*min/wk	5376 (347–14,166)	5576 (2826–7812)	0.974

ISSN: 1471-2407