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Table 2 Sensitivity of colon cancer spheroid cells and primary cultured cells to chemotherapeutic drugs

From: Long intergenic non-protein-coding RNA 1567 (LINC01567) acts as a “sponge” against microRNA-93 in regulating the proliferation and tumorigenesis of human colon cancer stem cells

  IC50 (mg/L)  
Drug TPSC PCC Fold difference
Adriamycin 36.5 ± 2.3** 2.1 ± 0.2 17.4
Paclitaxel 32.0 ± 2.4** 2.3 ± 0.3 13.9
Mitomycin 0.93 ± 0.04** 0.22 ± 0.02 4.2
Etoposide 10.2 ± 0.3** 3.4 ± 0.2 3.0
Cisplatin 10.5 ± 0.6* 4.1 ± 0.3 2.6
Cytarabine 27.7 ± 1.7* 13.9 ± 0.8 2.0
Fluorouracil 50.5 ± 4.1* 33.2 ± 2.2 1.5
  1. **P < 0.01; *P < 0.05; IC50: The half maximal inhibitory concentration