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Table 2 Sensitivity of colon cancer spheroid cells and primary cultured cells to chemotherapeutic drugs

From: Long intergenic non-protein-coding RNA 1567 (LINC01567) acts as a “sponge” against microRNA-93 in regulating the proliferation and tumorigenesis of human colon cancer stem cells

 

IC50 (mg/L)

 

Drug

TPSC

PCC

Fold difference

Adriamycin

36.5 ± 2.3**

2.1 ± 0.2

17.4

Paclitaxel

32.0 ± 2.4**

2.3 ± 0.3

13.9

Mitomycin

0.93 ± 0.04**

0.22 ± 0.02

4.2

Etoposide

10.2 ± 0.3**

3.4 ± 0.2

3.0

Cisplatin

10.5 ± 0.6*

4.1 ± 0.3

2.6

Cytarabine

27.7 ± 1.7*

13.9 ± 0.8

2.0

Fluorouracil

50.5 ± 4.1*

33.2 ± 2.2

1.5

  1. **P < 0.01; *P < 0.05; IC50: The half maximal inhibitory concentration
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BMC Cancer

ISSN: 1471-2407

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