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Fig. 1 | BMC Cancer

Fig. 1

From: MicroRNA-195 acts as an anti-proliferative miRNA in human melanoma cells by targeting Prohibitin 1

Fig. 1

MicroRNA-195 is down-regulated and PHB1 is up-regulated in patient and melanoma cell lines. a Scatter plot of the RNA Sequence data (TCGA) of 341 samples from melanoma patients compared to normal skin samples. The red line indicates an inverse correlation of expression between the samples for miR-195 and PHB1 genes (Pearson’s r = −0.23; P ≤ 0.001). b MicroRNA-195 is down-regulated (open columns down) and PHB1 up-regulated (full columns up) in 12/12 melanoma cell lines evaluated by RT-qPCR compared to melanocytes (NGM cells) using 2(− ∆∆ Ct) method. TCGA data are reported as means ± SD of relative quantification Log2 base values

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