TY - JOUR AU - Siegel, R. AU - Miller, K. AU - Jemal, A. PY - 2015 DA - 2015// TI - Cancer statistics, 2015 JO - CA Cancer J Clin [Internet] VL - 65 UR - https://doi.org/10.3322/caac.21254 DO - 10.3322/caac.21254 ID - Siegel2015 ER - TY - JOUR AU - Siegel, R. AU - Miller, K. AU - Jemal, A. PY - 2016 DA - 2016// TI - Cancer statistics, 2016 JO - CA Cancer J Clin VL - 66 UR - https://doi.org/10.3322/caac.21332 DO - 10.3322/caac.21332 ID - Siegel2016 ER - TY - JOUR AU - Torre, L. A. AU - Bray, F. AU - Siegel, R. L. AU - Ferlay, J. AU - Lortet-tieulent, J. AU - Jemal, A. PY - 2015 DA - 2015// TI - Global cancer statistics, 2012 JO - CA a cancer J Clin [Internet] VL - 65 UR - https://doi.org/10.3322/caac.21262 DO - 10.3322/caac.21262 ID - Torre2015 ER - TY - JOUR AU - Boyle, P. PY - 2012 DA - 2012// TI - Triple-negative breast cancer: epidemiological considerations and recommendations JO - Ann Oncol [Internet] VL - 23 ID - Boyle2012 ER - TY - JOUR AU - Hurvitz, S. AU - Mead, M. PY - 2016 DA - 2016// TI - Triple-negative breast cancer JO - Curr Opin Obs Gynecol [Internet] VL - 28 ID - Hurvitz2016 ER - TY - JOUR AU - Turner, N. AU - Moretti, E. AU - Siclari, O. AU - Migliaccio, I. AU - Santarpia, L. AU - D’Incalci, M. PY - 2013 DA - 2013// TI - Targeting triple negative breast cancer: is p53 the answer? JO - Cancer Treat Rev [Internet] Elsevier Ltd VL - 39 UR - https://doi.org/10.1016/j.ctrv.2012.12.001 DO - 10.1016/j.ctrv.2012.12.001 ID - Turner2013 ER - TY - JOUR AU - Koboldt, D. C. AU - Fulton, R. S. AU - McLellan, M. D. AU - Schmidt, H. AU - Kalicki-Veizer, J. AU - McMichael, J. F. PY - 2012 DA - 2012// TI - Comprehensive molecular portraits of human breast tumours JO - Nature [Internet] VL - 490 UR - https://doi.org/10.1038/nature11412 DO - 10.1038/nature11412 ID - Koboldt2012 ER - TY - STD TI - O’Sullivan CC, Moon DH, Kohn EC, Lee J, Sullivan CCO, Moon DH, et al. Beyond breast and ovarian cancers: PARP inhibitors for BRCA mutation-associated and BRCA-like solid tumors. Front Oncol [Internet]. 2014;4:42. Available from: http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=3937815&tool=pmcentrez&rendertype=abstract ID - ref8 ER - TY - STD TI - Basu B, Sandhu SK, De Bono JS. PARP inhibitors: mechanism of action and their potential role in the prevention and treatment of cancer. Drugs 2012;72:1579–1590. ID - ref9 ER - TY - JOUR AU - Bayraktar, S. AU - Glück, S. PY - 2012 DA - 2012// TI - Systemic therapy options in BRCA mutation-associated breast cancer JO - Breast Cancer Res Treat VL - 135 UR - https://doi.org/10.1007/s10549-012-2158-6 DO - 10.1007/s10549-012-2158-6 ID - Bayraktar2012 ER - TY - JOUR AU - Petrelli, F. AU - Coinu, A. AU - Borgonovo, K. AU - Cabiddu, M. AU - Ghilardi, M. AU - Lonati, V. PY - 2014 DA - 2014// TI - The value of platinum agents as neoadjuvant chemotherapy in triple-negative breast cancers: a systematic review and meta-analysis JO - Breast Cancer Res Treat VL - 144 UR - https://doi.org/10.1007/s10549-014-2876-z DO - 10.1007/s10549-014-2876-z ID - Petrelli2014 ER - TY - JOUR AU - Carvalho, M. R. AU - Lima, D. AU - Reis, R. L. AU - Correlo, V. M. AU - Oliveira, J. M. PY - 2015 DA - 2015// TI - Evaluating biomaterial- and microfluidic-based 3D tumor models JO - Trends Biotechnol [Internet] Elsevier Ltd VL - 33 UR - https://doi.org/10.1016/j.tibtech.2015.09.009 DO - 10.1016/j.tibtech.2015.09.009 ID - Carvalho2015 ER - TY - JOUR AU - Shen, K. AU - Qi, Y. AU - Song, N. AU - Tian, C. AU - Rice, S. D. AU - Gabrin, M. J. PY - 2012 DA - 2012// TI - Cell line derived multi-gene predictor of pathologic response to neoadjuvant chemotherapy in breast cancer: a validation study on US oncology 02-103 clinical trial JO - BMC Med Genomics [Internet] VL - 5 UR - https://doi.org/10.1186/1755-8794-5-51 DO - 10.1186/1755-8794-5-51 ID - Shen2012 ER - TY - JOUR AU - Abbott, A. PY - 2003 DA - 2003// TI - Biology ’ s new dimension JO - Nature [Internet] VL - 424 UR - https://doi.org/10.1038/424870a DO - 10.1038/424870a ID - Abbott2003 ER - TY - JOUR AU - Lee, G. Y. AU - Kenny, P. A. AU - Lee, E. H. AU - Bissell, M. J. PY - 2010 DA - 2010// TI - Three-dimensional culture models of normal and malignant breast epithelial cells JO - Nat Methods VL - 4 UR - https://doi.org/10.1038/nmeth1015 DO - 10.1038/nmeth1015 ID - Lee2010 ER - TY - JOUR AU - Dhimolea, E. AU - Maffini, M. V. AU - Soto, A. M. AU - Sonnenschein, C. PY - 2010 DA - 2010// TI - The role of collagen reorganization on mammary epithelial morphogenesis in a 3D culture model JO - Biomaterials [Internet] Elsevier Ltd VL - 31 UR - https://doi.org/10.1016/j.biomaterials.2010.01.077 DO - 10.1016/j.biomaterials.2010.01.077 ID - Dhimolea2010 ER - TY - JOUR AU - Rijal, G. AU - Li, W. PY - 2016 DA - 2016// TI - 3D scaffolds in breast cancer research JO - Biomaterials [Internet] Elsevier Ltd VL - 81 UR - https://doi.org/10.1016/j.biomaterials.2015.12.016 DO - 10.1016/j.biomaterials.2015.12.016 ID - Rijal2016 ER - TY - JOUR AU - Kenny, P. A. AU - Lee, G. Y. AU - Myers, C. A. AU - Neve, R. M. AU - Semeiks, J. R. AU - Spellman, P. T. PY - 2007 DA - 2007// TI - The morphologies of breast cancer cell lines in three-dimensional assays correlate with their profiles of gene expression JO - Mol Oncol [Internet] VL - 1 UR - https://doi.org/10.1016/j.molonc.2007.02.004 DO - 10.1016/j.molonc.2007.02.004 ID - Kenny2007 ER - TY - JOUR AU - Vahidnezhad, H. AU - Youssefian, L. AU - Jeddi-Tehrani, M. AU - Akhondi, M. M. AU - Rabbani, H. AU - Shokri, F. PY - 2009 DA - 2009// TI - Modeling breast acini in tissue culture for detection of malignant phenotype reversion to non-malignant phenotype JO - Iran Biomed J [Internet] VL - 13 ID - Vahidnezhad2009 ER - TY - JOUR AU - Barcellos-Hoff, M. H. AU - Aggeler, J. AU - Ram, T. G. AU - Bissell, M. J. PY - 1989 DA - 1989// TI - Functional differentiation and alveolar morphogenesis of primary mammary cultures on reconstituted basement membrane JO - Development VL - 105 ID - Barcellos-Hoff1989 ER - TY - JOUR AU - Sung, K. E. AU - Su, X. AU - Berthier, E. AU - Pehlke, C. AU - Friedl, A. AU - Beebe, D. J. PY - 2013 DA - 2013// TI - Understanding the impact of 2D and 3D fibroblast cultures on in vitro breast cancer models JO - PLoS One VL - 8 ID - Sung2013 ER - TY - JOUR AU - Mi, Z. AU - Holmes, F. A. AU - Hellerstedt, B. AU - Pippen, J. AU - Collea, R. AU - Backner, A. PY - 2008 DA - 2008// TI - Feasibility assessment of a Chemoresponse assay to predict pathologic response in Neoadjuvant chemotherapy for breast cancer patients JO - Anticancer Res [Internet] VL - 28 ID - Mi2008 ER - TY - JOUR AU - Jeon, J. S. AU - Bersini, S. AU - Gilardi, M. AU - Dubini, G. AU - Charest, J. L. AU - Moretti, M. PY - 2015 DA - 2015// TI - Human 3D vascularized organotypic microfluidic assays to study breast cancer cell extravasation JO - Proc Natl Acad Sci [Internet] VL - 112 UR - https://doi.org/10.1073/pnas.1417115112 DO - 10.1073/pnas.1417115112 ID - Jeon2015 ER - TY - JOUR AU - Trietsch, S. J. AU - Israëls, G. D. AU - Joore, J. AU - Hankemeier, T. AU - Vulto, P. PY - 2013 DA - 2013// TI - Microfluidic titer plate for stratified 3D cell culture JO - Lab Chip [Internet] VL - 13 UR - https://doi.org/10.1039/c3lc50210d DO - 10.1039/c3lc50210d ID - Trietsch2013 ER - TY - STD TI - van Duinen V, Trietsch SJ, Joore J, Vulto P, Hankemeier T. Microfluidic 3D cell culture: from tools to tissue models. Curr Opin Biotechnol [Internet] Elsevier Ltd; 2015;35:118–126. Available from: http://www.sciencedirect.com/science/article/pii/S0958166915000713?via%3Dihub. UR - http://www.sciencedirect.com/science/article/pii/S0958166915000713?via%3Dihub ID - ref25 ER - TY - JOUR AU - Zervantonakis, I. K. AU - Hughes-Alford, S. K. AU - Charest, J. L. AU - Condeelis, J. S. AU - Gertler, F. B. AU - Kamm, R. D. PY - 2012 DA - 2012// TI - Three-dimensional microfluidic model for tumor cell intravasation and endothelial barrier function JO - Proc Natl Acad Sci VL - 109 UR - https://doi.org/10.1073/pnas.1210182109 DO - 10.1073/pnas.1210182109 ID - Zervantonakis2012 ER - TY - JOUR AU - Montanez-Sauri, S. I. AU - Sung, K. E. AU - Berthier, E. AU - Beebe, D. J. PY - 2013 DA - 2013// TI - Enabling screening in 3D microenvironments: probing matrix and Stromal effects on the morphology and proliferation of T47D breast carcinoma cells JO - Integr Biol [Internet] VL - 5 UR - https://doi.org/10.1039/c3ib20225a DO - 10.1039/c3ib20225a ID - Montanez-Sauri2013 ER - TY - JOUR AU - Polacheck, W. J. AU - Charest, J. L. AU - Kamm, R. D. PY - 2011 DA - 2011// TI - Interstitial flow influences direction of tumor cell migration through competing mechanisms JO - Proc Natl Acad Sci U S A [Internet] VL - 108 UR - https://doi.org/10.1073/pnas.1103581108 DO - 10.1073/pnas.1103581108 ID - Polacheck2011 ER - TY - JOUR AU - Shields, J. D. AU - Fleury, M. E. AU - Yong, C. AU - Tomei, A. A. AU - Randolph, G. J. AU - Swartz, M. A. PY - 2007 DA - 2007// TI - Autologous Chemotaxis as a mechanism of tumor cell homing to Lymphatics via interstitial flow and Autocrine CCR7 signaling JO - Cancer Cell VL - 11 UR - https://doi.org/10.1016/j.ccr.2007.04.020 DO - 10.1016/j.ccr.2007.04.020 ID - Shields2007 ER - TY - JOUR AU - Shieh, A. C. AU - Rozansky, H. A. AU - Hinz, B. AU - Swartz, M. A. PY - 2011 DA - 2011// TI - Tumor cell invasion is promoted by interstitial flow-induced matrix priming by stromal fibroblasts JO - Cancer Res VL - 71 UR - https://doi.org/10.1158/0008-5472.CAN-10-1513 DO - 10.1158/0008-5472.CAN-10-1513 ID - Shieh2011 ER - TY - JOUR AU - Sung, K. E. AU - Yang, N. AU - Pehlke, C. AU - Keely, P. J. AU - Eliceiri, K. W. AU - Friedl, A. PY - 2011 DA - 2011// TI - Transition to invasion in breast cancer: a microfluidic in vitro model enables examination of spatial and temporal effects JO - Integr Biol [Internet] VL - 3 UR - https://doi.org/10.1039/C0IB00063A DO - 10.1039/C0IB00063A ID - Sung2011 ER - TY - STD TI - Junaid A, Mashaghi A, Hankemeier T, Vulto P. An End-User Perspective on Organ-on-a-Chip: Assays and Usability Aspects. Curr. Opin. Biomed. Eng. [Internet]. Elsevier Inc.; 2017; Available from: https://doi.org/10.1016/j.cobme.2017.02.002 ID - ref32 ER - TY - JOUR AU - Su, G. AU - Sung, K. E. AU - Beebe, D. J. AU - Friedl, A. PY - 2012 DA - 2012// TI - Functional screen of Paracrine signals in breast carcinoma fibroblasts JO - PLoS One VL - 7 UR - https://doi.org/10.1371/annotation/01ebf0b5-ccd3-494d-b577-170981f7bc36 DO - 10.1371/annotation/01ebf0b5-ccd3-494d-b577-170981f7bc36 ID - Su2012 ER - TY - JOUR AU - Moreno, E. L. AU - Hachi, S. AU - Hemmer, K. AU - Trietsch, S. J. AU - Baumuratov, A. S. AU - Hankemeier, T. PY - 2015 DA - 2015// TI - Differentiation of neuroepithelial stem cells into functional dopaminergic neurons in 3D microfluidic cell culture. Lab Chip [internet] JO - Royal Society of Chemistry VL - 15 ID - Moreno2015 ER - TY - JOUR AU - Wevers, N. R. AU - van Vught, R. AU - Wilschut, K. J. AU - Nicolas, A. AU - Chiang, C. AU - Lanz, H. L. PY - 2016 DA - 2016// TI - High-throughput compound evaluation on 3D networks of neurons and glia in a microfluidic platform JO - Sci Rep [Internet] VL - 6 UR - https://doi.org/10.1038/srep38856 DO - 10.1038/srep38856 ID - Wevers2016 ER - TY - STD TI - Jang M, Neuzil P, Volk T, Manz A, Kleber A. On-chip three-dimensional cell culture in phaseguides improves hepatocyte functions in vitro. Biomicrofluidics [Internet]. 2015;9:34113. Available from: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4482807/. UR - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4482807/ ID - ref36 ER - TY - JOUR AU - Goetz, M. P. AU - Kalari, K. R. AU - Suman, V. J. AU - Moyer, A. M. AU - Yu, J. AU - Visscher, D. W. PY - 2017 DA - 2017// TI - Tumor sequencing and patient-derived Xenografts in the Neoadjuvant treatment of breast cancer JO - JNCI J Natl Cancer Inst VL - 109 UR - https://doi.org/10.1093/jnci/djw306 DO - 10.1093/jnci/djw306 ID - Goetz2017 ER - TY - JOUR AU - Abràmoff, M. D. AU - Magalhães, P. J. AU - Ram, S. J. PY - 2004 DA - 2004// TI - Image processing with imageJ JO - Biophoton Int VL - 11 ID - Abràmoff2004 ER - TY - JOUR AU - Vulto, P. AU - Podszun, S. AU - Meyer, P. AU - Hermann, C. AU - Manz, A. AU - Urban, G. a. PY - 2011 DA - 2011// TI - Phaseguides: a paradigm shift in microfluidic priming and emptying JO - Lab Chip VL - 11 UR - https://doi.org/10.1039/c0lc00643b DO - 10.1039/c0lc00643b ID - Vulto2011 ER - TY - STD TI - Lehmann BDB, Bauer JaJ, Chen X, Sanders ME, Chakravarthy a B, Shyr Y, et al. Identification of human triple-negative breast cancer subtypes and preclinical models for selection of targeted therapies. J Clin Invest [Internet]. 2011;121:2750–2767. Available from: http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=3127435&tool=pmcentrez&rendertype=abstract%5Cnhttp://www.ncbi.nlm.nih.gov/pmc/articles/pmc3127435/ ID - ref40 ER - TY - JOUR AU - Kenny, P. A. AU - Lee, G. Y. AU - Myers, C. A. AU - Neve, R. M. AU - Semeiks, J. R. AU - Spellman, P. T. PY - 2007 DA - 2007// TI - The morphologies of breast cancer cell lines in three-dimensional assays correlate with their profiles of gene expression JO - Mol Oncol VL - 1 UR - https://doi.org/10.1016/j.molonc.2007.02.004 DO - 10.1016/j.molonc.2007.02.004 ID - Kenny2007 ER - TY - STD TI - Farris FF, Dedrick RL, King FG. Cisplatin pharmacokinetics: applications of a physiological model. Toxicol Lett [Internet], Available from. 1988;43:117–37. http://www.ncbi.nlm.nih.gov/pubmed/3051521 UR - http://www.ncbi.nlm.nih.gov/pubmed/3051521 ID - ref42 ER - TY - STD TI - Huyck L, Ampe C, Van Troys M. The XTT cell proliferation assay applied to cell layers embedded in three-dimensional matrix. Assay Drug Dev Technol 2012;10:382–392. ID - ref43 ER - TY - STD TI - Palla V, Karaolanis G, Katafigiotis I, Anastasiou I, Patapis P, Dimitroulis D, et al. gamma-H2AX : Can it be established as a classical cancer prognostic factor? Tumour Biol. 2017;March:1–11. ID - ref44 ER -