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Table 3 Comparison of doses to pelvic bone marrow and its subsistes (defined with outer bone contours) and to inactive bone marrow and its subsites (defined with 18FDG-PET) among the 4 plans

From: Incorporating 18FDG-PET-defined pelvic active bone marrow in the automatic treatment planning process of anal cancer patients undergoing chemo-radiation

   Plan A Plan B Plan C Plan D p ≤ 0.05 ANOVA Fisher-Hayter test
Structure Parameter Mean SD(+/−) Mean SD(+/−) Mean SD(+/−) Mean SD(+/−)   
PBM D max 53.50 2.30 53.57 2.20 53.55 2.13 53.73 2.09 NS  
D mean 25.72 2.44 23.30 2.38 23.25 2.81 23.58 2.74 NS  
LSBM D max 48.56 2.17 48.83 1.79 49.21 1.88 49.27 1.95 NS  
D mean 30.88 3.68 26.44 3.85 26.52 3.97 26.97 3.80 0.038 A vs B and C
IBM D max 48.64 3.04 48.89 3.17 49.35 2.99 49.16 3.21 NS  
D mean 22.16 1.59 21.57 1.48 20.48 2.31 20.84 2.38 NS  
V 30 24.58 4.74 24.65 3.76 21.14 6.60 22.06 7.36 NS  
V 40 7.13 3.03 6.34 2.75 6.65 2.42 7.18 2.70 NS  
V 45 1.15 1.90 1.09 2.15 1.49 1.53 1.45 1.81 NS  
LPBM D max 53.60 2.45 53.76 2.33 53.89 2.33 54.01 2.27 NS  
D mean 25.99 4.12 23.76 4.36 24.46 4.62 24.60 4.48 NS  
1- ACTPBM D max 53.38 2.25 53.38 2.12 53.36 2.05 53.55 2.09 NS  
D mean 22.70 3.58 20.21 3.40 21.18 3.92 21.56 3.79 NS  
1-ACTLSBM D max 48.32 2.17 48.60 1.85 48.94 1.90 48.95 2.00 NS  
D mean 28.95 4.43 24.00 4.88 25.12 3.93 25.83 3.74 NS  
1-ACTIBM D max 48.60 3.06 48.70 3.32 49.24 3.07 49.06 3.17 NS  
D mean 19.98 3.65 18.96 3.59 19.05 3.71 19.43 3.77 NS  
1-ACTLPBM D max 53.28 2.20 53.27 2.04 53.36 2.05 53.38 2.01 NS  
D mean 21.85 4.16 19.60 3.88 20.77 4.82 21.06 4.60 NS  
  1. Legend: D max maximal dose, D mean mean dose, SD standard deviation, V 30,40,45 relative volume receiving 30,40,45 Gy, PBM pelvic bone marrow, LSBM lumbar-sacral bone marrow, IBM iliac bone marrow, LPBM lower pelvis bone marrow,ACT active, A, B, C plan A, B, C, NS non significant