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Table 6 the sensitivity of HepG2 or HepG2/ADR cells to antitumor agents

From: A novel chemotherapeutic sensitivity-testing system based on collagen gel droplet embedded 3D–culture methods for hepatocellular carcinoma

Compounds 2-D HepG2 2-D HepG2/ADR 3-D HepG2
IC 50 values (μg/ml)
5-PU 0.45 ± 0.06 0.77 ± 0.33 0.83 ± 0.45
PAC 0.01 ± 0.00 0.02 ± 0.01 0.03 ± 0.02
CDDP 0.26 ± 0.23 1.39 ± 0.40 1.15 ± 0.75
EPI 0.02 ± 0.01 0.16 ± 0.04 0.09 ± 0.03
L-OHP 0.55 ± 0.12 1.85 ± 0.44 1.76 ± 0.44