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Table 6 the sensitivity of HepG2 or HepG2/ADR cells to antitumor agents

From: A novel chemotherapeutic sensitivity-testing system based on collagen gel droplet embedded 3D–culture methods for hepatocellular carcinoma

Compounds

2-D HepG2

2-D HepG2/ADR

3-D HepG2

IC 50 values (μg/ml)

5-PU

0.45 ± 0.06

0.77 ± 0.33

0.83 ± 0.45

PAC

0.01 ± 0.00

0.02 ± 0.01

0.03 ± 0.02

CDDP

0.26 ± 0.23

1.39 ± 0.40

1.15 ± 0.75

EPI

0.02 ± 0.01

0.16 ± 0.04

0.09 ± 0.03

L-OHP

0.55 ± 0.12

1.85 ± 0.44

1.76 ± 0.44

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BMC Cancer

ISSN: 1471-2407

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