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Table 1 Baseline demographic and clinical characteristics

From: Prospective study of 11C–methionine PET for distinguishing between recurrent brain metastases and radiation necrosis: limitations of diagnostic accuracy and long-term results of salvage treatment

Characteristic

Value

Sex (male/female)

19/13

Agea (years), median (range)

65 (14–87)

Primary cancer

 

 Non-small cell lung cancer

 

  EGFR wild-type

14

  EGFR mutant

5

 Small cell lung cancer

3

 Breast cancer

 

  HER2-positive

4

  HER2-negative

1

 Gastrointestinal cancer

2

 Oesophageal cancer

1

 Sinonasal adenoid cystic carcinoma

1

 Rhabdomyosarcoma

1

KPSa, median (range)

90 (50–100)

Neurological deficitsa

24 (75%)

RTOG-RPA Classa (I/II/III)

8/18/6

Multiple BMa

16 (50%)

Prior radiotherapy (per lesion)

 

  Proton therapy

1

  SRS

21

  WBRT + SRS

3

  SRS × 2

9

  SRS × 3

2

  SRS × 4

1

Time from primary radiotherapy to MET-PET (months), median (range)

18.8 (4–120)

  1. EGFR epidermal growth factor receptor, HER human epidermal growth factor, KPS Karnofsky performance status, RTOG radiation treatment oncology group, RPA recursive partitioning analysis, BM brain metastases, aupdated status at the time of MET-PET, SRS stereotactic radiosurgery, WBRT whole brain radiotherapy, MET-PET 11C–methionine positron emission tomography