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Table 1 Synergism studies between NVP-AEW541 and lapatinib

From: Inhibition of PI3K/Akt/mTOR overcomes cisplatin resistance in the triple negative breast cancer cell line HCC38

Lapatinib [μM]
AEW541 [μM] 1 2 2.5 3 3.5
0.5 a a 0.76 0.52 0.46
1 a 0.58 0.51 0.44 0.42
1.5 0.96 0.59 0.58 0.51 0.49
2 0.46 0.42 0.46 0.49 0.52
3 0.69 0.57 0.56 0.68 0.64
  1. a fraction affected <0.2