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Table 1 Synergism studies between NVP-AEW541 and lapatinib

From: Inhibition of PI3K/Akt/mTOR overcomes cisplatin resistance in the triple negative breast cancer cell line HCC38

Lapatinib [μM]

AEW541 [μM]

1

2

2.5

3

3.5

0.5

a

a

0.76

0.52

0.46

1

a

0.58

0.51

0.44

0.42

1.5

0.96

0.59

0.58

0.51

0.49

2

0.46

0.42

0.46

0.49

0.52

3

0.69

0.57

0.56

0.68

0.64

  1. a fraction affected <0.2