| HR | P | CI |
---|
PTTG1IP | | NS. | |
---|
Securin | 2.5 | <0.001 | 1.5-4.1 |
Tumour size | 1.3 | 0.001 | 1.1-1.5 |
Nodal status | 2.6 | <0.001 | 1.6-4.1 |
Histological grade |
grade 1 vs 2-3 | | NS. | |
grade 3 vs 1-2 | | NS. | |
Intrinsic classification |
Luminal vs others | | NS. | |
Triple─ vs others | | NS. | |
-
Abbreviations: HR Hazard ratio, P P-value of Wilcoxon's rank sum test, CI = 95% confidence interval, NS No statistical significance
- The analysis is based on 401 breast carcinoma patients with up to 22-year follow-up
-
aAnalysis has been performed on material divided into subgroups with favourable vs
- unfavourable prognosis as follows:
- PTTG1IP stratified into positive vs negative immunoexpression
- Securin stratified into low vs high immunoexpression (<10% vs ≥10% positive cancer cells)
- Tumour size stratified into small vs large (≤2cm vs >2cm in diameter)
- Nodal status stratified into axillary lymph node negative vs positive
- Histological grade stratified into grades 1, 2 and 3
- Intrinsic classification stratified into luminal, Her2-amplified and triple-negative