Skip to main content

Table 3 Numbers of microRNAs (out of the indicated numbers considered multimodal at each site) classified with respect to the tumor-normal test of differential expression as: (b, “blue”) overall significant, with significant directional agreement in one factor level and NS in the other; (g, “green”) overall NS, but significant in only one factor level; (o, “orange”) overall NS, and significant in opposite directions for factor levels; and (y, “yellow”) overall significant, with significant directional agreement in one factor level but significant in the opposite direction in the other factor level

From: Identifying factors associated with the direction and significance of microRNA tumor-normal expression differences in colorectal cancer

 

Proximal (of 122)

Distal (of 123)

Rectal (of 276)

Factor

b

g

o

y

b

g

o

y

b

g

o

y

MSI

27

  

1

62

  

1

186

  

4

CIMP

19

  

1

29

   

64

1

  

BRAF

13

3

 

1

58

   

176

   

TP53

16

   

10

   

28

5

  

KRAS

21

2

  

14

   

29

3

1

 

STAGE_D

32

1

  

12

1

  

53

2

  

STAGE_L

23

   

10

   

19

3

1

 

STAGE_R

19

   

15

   

21

1

  

AJCC_1

40

2

  

7

1

  

19

3

  

AJCC_2

18

   

10

   

16

2

1

 

AJCC_3

28

2

  

8

1

  

41

6

  

SEX

23

3

  

6

   

12

1

  

DIFF_NA

55

   

42

       

DIFF_WELL

37

   

30

       

DIFF_MOD

13

   

16

       

DIFF_POOR

21

1

  

27

       

VITAL_ALIVE

16

   

15

5

  

27

1

  

SURV5YRS

17

   

21

4

2

 

18

1

  

COD_CRC

19

1

  

3

6

  

67

9

  

ALCOHOL_reg

11

   

7

   

51

5

  

WINE_any

9

1

  

12

1

  

78

8

1

1

LIQUOR_any

13

1

  

14

3

  

68

5

1

1

BEER_any

16

2

  

11

   

56

2

  

CIG_ever

24

5

  

4

   

36

5

  

CIG_current

23

   

17

1

  

69

8

1

 

CIG_former

19

4

  

5

   

28

1

  

ESTROGEN

12

1

  

11

   

46

4

  

BMI_normal

9

   

10

2

  

33

4

  

BMI_overweight

17

4

  

10

   

30

1

  

BMI_obese

18

   

22

   

68

2

  

BMI_extreme

66

   

58

   

150

1

 Â