Identifying factors associated with the direction and significance of microRNA tumor-normal expression differences in colorectal cancer

Table 2 Numbers of microRNAs classified as up-regulated, down-regulated, or not significantly differentially expressed (NS) in tumor relative to normal, at various site / factor level combinations

Factor Level		Overall
0	1	Down	NS	Up	Superscripts (and totals) – colors named here are used in later tables, figures, and additional files ^b (“blue”) overall significance, with agreement in one factor level and NS in the other (2759) ^g (“green”) overall NS, but significant in only one factor level (142) ^o (“orange”) overall NS, and significant in opposite directions for factor levels (8) ^p (“purple”) agreement in both factor levels (direction or NS), but different from overall (NS or direction) (223) ^y (“yellow”) overall significance, with agreement in one factor level but opposite direction in the other factor level (10)
Down	Down	4782	1 ^p	^p
Down	NS	1758 ^b	44 ^g
Down	Up	2 ^y	6 ^o	^y
NS	Down	387 ^b	40 ^g
NS	NS	126 ^p	1730	96 ^p
NS	Up		34 ^g	157 ^b
Up	Down	^y	2 ^o	8 ^y
Up	NS		24 ^g	457 ^b
Up	Up	^p	^p	2217

ISSN: 1471-2407