Fig. 2

Representative results for outcomes of interest – overall significance, with agreement in one factor level and NS in the other (a-c; blue); overall NS, but significant in only one factor level (d-f; green); overall NS, and significant in opposite directions for factor levels (g-i; orange); agreement in both factor levels (direction or NS), but different from overall (NS or direction) (j-l; purple); and overall significance, with agreement in one factor level but opposite direction in the other factor level (m-o; yellow)