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Table 4 Multivariate analysis of the prognostic factors of disease-free survival in colorectal cancer patients

From: Oestrogen receptor beta isoform expression in sporadic colorectal cancer, familial adenomatous polyposis and progressive stages of colorectal cancer

Variable N HR p 95% CI
T stage (TNM)
 T1-T2 47 1.0 0.003 2.88–170.7
 T3-T4 51 22.1
N stage (TNM)
 N0 59 1.0 0.034 1.09–8.41
 N+ 39 3.03
Primer Pair 2 – ERβ1 and ERβ5 isoforms (loss of relative gene expression (log2)*
  ≤ −4.5 65 1.0 0.002 1.69–9.84
  > −4.5 33 4.08
  1. *The cutoff for relative gene expression (log2) was determined using the log-rank test (maximally selected rank statistics in R) [24]