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Table 4 Multivariate analysis of the prognostic factors of disease-free survival in colorectal cancer patients

From: Oestrogen receptor beta isoform expression in sporadic colorectal cancer, familial adenomatous polyposis and progressive stages of colorectal cancer

Variable

N

HR

p

95% CI

T stage (TNM)

 T1-T2

47

1.0

0.003

2.88–170.7

 T3-T4

51

22.1

N stage (TNM)

 N0

59

1.0

0.034

1.09–8.41

 N+

39

3.03

Primer Pair 2 – ERβ1 and ERβ5 isoforms (loss of relative gene expression (log2)*

  ≤ −4.5

65

1.0

0.002

1.69–9.84

  > −4.5

33

4.08

  1. *The cutoff for relative gene expression (log2) was determined using the log-rank test (maximally selected rank statistics in R) [24]