Table 4 Positive Predictive Values (PPV) of self-reported breast cancer characteristics stratified by age at diagnosis, Sister Study 2003-2014a
35–54 (n = 536) | 55–64 (n = 744) | ≥65 (n = 728) | |||||||
|---|---|---|---|---|---|---|---|---|---|
Breast cancer characteristic | Medical record (%)b | Self-report (%)b | PPV (%) | Medical record (%)b | Self-report (%)b | PPV (%) | Medical record (%)b | Self-report (%)b | PPV (%) |
Invasiveness | |||||||||
Invasive | 396 (74) | 340 (65) | 99.4 | 554 (75) | 448 (63) | 99.3 | 583 (80) | 403 (60) | 99.3 |
In situ | 139 (26) | 181 (35) | 75.1 | 188 (25) | 263 (37) | 69.7 | 145 (20) | 267 (40) | 51.3 |
Unknown | 1 | 15 | 2 | 33 | 0 | 58 | |||
Locationc | |||||||||
Ductal (any) | 467 (88) | 426 (85) | 98.6 | 669 (90) | 586 (88) | 99.1 | 668 (92) | 550 (90) | 98.9 |
Lobular only | 64 (12) | 76 (15) | 76.0 | 71 (10) | 78 (12) | 76.9 | 55 (8) | 61 (10) | 73.8 |
Unknown | 3 | 32 | 2 | 78 | 4 | 116 | |||
Stage | |||||||||
0 | 139 (26) | 159 (32) | 78.0 | 187 (25) | 214 (33) | 75.5 | 145 (20) | 190 (31) | 60.5 |
I | 241 (45) | 183 (37) | 92.8 | 367 (50) | 258 (39) | 91.9 | 427 (59) | 271 (45) | 91.9 |
II | 116 (22) | 114 (23) | 71.1 | 141 (19) | 134 (20) | 67.2 | 123 (17) | 104 (17) | 65.4 |
III/IV | 38 (7) | 37 (8) | 75.7 | 46 (6) | 52 (8) | 73.1 | 33 (5) | 39 (6) | 64.1 |
Unknown | 2 | 43 | 3 | 86 | 0 | 124 | |||
Among medically confirmed invasive cases:d | |||||||||
ER | |||||||||
Positive | 322 (84) | 305 (81) | 98.7 | 454 (83) | 406 (82) | 99.0 | 501 (89) | 393 (85) | 99.5 |
Negative | 63 (16) | 73 (19) | 82.6 | 90 (17) | 92 (18) | 87.6 | 64 (11) | 69 (15) | 77.3 |
Unknown | 11 | 18 | 10 | 56 | 18 | 121 | |||
PR | |||||||||
Positive | 293 (76) | 207 (65) | 99.5 | 375 (69) | 213 (57) | 99.1 | 413 (74) | 223 (64) | 98.2 |
Negative | 91 (24) | 112 (35) | 69.7 | 166 (31) | 163 (43) | 72.0 | 147 (26) | 127 (36) | 73.0 |
Unknown | 12 | 77 | 13 | 178 | 23 | 233 | |||
HER2 | |||||||||
Positive | 49 (13) | 64 (20) | 71.7 | 65 (12) | 90 (23) | 67.0 | 53 (10) | 78 (22) | 60.0 |
Negative | 324 (87) | 263 (80) | 98.0 | 458 (88) | 310 (78) | 100 | 490 (90) | 272 (78) | 99.2 |
Unknown | 23 | 69 | 31 | 154 | 40 | 233 | |||