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Table 3 Positive Predictive Values (PPV) of self-reported breast cancer characteristics stratified by race/ethnicity, Sister Study 2003-2014a

From: Validity of self-reported breast cancer characteristics in a nationwide cohort of women with a family history of breast cancer

  Non-Hispanic white (n = 1774) Non-Hispanic black (n = 111) Hispanic (n = 66)
Breast cancer characteristic Medical record (%)b Self-report (%)b PPV (%) Medical record (%)b Self-report (%)b PPV (%) Medical record (%)b Self-report (%)b PPV (%)
Invasiveness
 Invasive 1360 (77) 1074 (64) 99.3 77 (70) 48 (48) 100 51 (77) 32 (53) 100
 In situ 412 (23) 615 (36) 65.3 33 (30) 51 (52) 62.7 15 (23) 28 (47) 46.4
 Unknown 2 85   1 12   0 6  
Locationc
 Ductal (any) 1586 (90) 1380 (88) 99.0 106 (96) 87 (92) 100 60 (91) 47 (85) 97.9
 Lobular only 175 (10) 196 (12) 77.0 4 (4) 8 (8) 42.9 6 (9) 8 (15) 62.5
 Unknown 8 193   1 16   0 11  
Stage
 0 411 (23) 488 (31) 72.2 33 (30) 39 (40) 71.8 15 (23) 20 (38) 50.0
 I 924 (52) 654 (42) 92.6 47 (43) 31 (32) 83.3 34 (52) 15 (29) 86.7
 II 333 (19) 317 (20) 68.8 23 (21) 17 (17) 64.7 15 (23) 10 (19) 60.0
 III/IV 102 (6) 102 (7) 75.5 7 (6) 11 (11) 54.5 2 (3) 7 (13) 28.6
 Unknown 4 213   1 13   0 14  
Among medically confirmed invasive cases:d
 ER
  Positive 1147 (87) 1011 (84) 99.5 55 (71) 38 (64) 94.7 43 (90) 31 (79) 96.8
  Negative 179 (13) 196 (16) 85.6 22 (29) 21 (36) 71.4 5 (10) 8 (21) 50.0
  Unknown 34 153   0 18   3 12  
 PR
  Positive 983 (75) 602 (64) 99.2 42 (55) 18 (40) 94.4 29 (62) 13 (45) 100
  Negative 335 (25) 342 (36) 71.4 35 (45) 27 (60) 74.1 18 (38) 16 (55) 66.7
  Unknown 42 416   0 32   4 22  
 HER2
  Positive 144 (11) 203 (21) 64.7 6 (8) 11 (24) 54.5 9 (19) 7 (26) 100
  Negative 1129 (89) 772 (79) 99.1 69 (92) 35 (76) 100 39 (81) 20 (74) 100
  Unknown 87 385   2 31   3 24  
  1. Abbreviation: PPV positive predictive value, ER estrogen receptor, PR progesterone receptor, HER2 human epidermal growth factor receptor 2
  2. aExcludes 43 who did not complete the questionnaire about breast cancer characteristics and 3 who reported on a different breast cancer event than the one abstracted from her medical records and excludes 56 who reported other race/ethnicity and 1 with missing data for race/ethnicity
  3. bData are reported as number (percentage) of women. Totals may not always equal 100% because of rounding
  4. cExcludes 5 cases that are not of ductal or lobular origin (phyllodes tumors)
  5. dER, PR, and HER2 analyses are restricted to 1360 non-Hispanic white, 77 non-Hispanic black, and 51 Hispanic cases confirmed as invasive breast cancer by medical records