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Table 4 SIR of second primary cancer by type of first primary cancer and age group at first diagnosis

From: The relative risk of second primary cancers in Austria’s western states: a retrospective cohort study

 

Age group at first diagnosis

 

15–49 years

50–64 years

65 years and over

First primary cancer

Obs.

SIR (95% CI)

Obs.

SIR (95% CI)

Obs.

SIR (95% CI)

Head/Neck/Larynx

42

2.35 (1.69–3.17)

189

2.21 (1.91–2.55)

103

1.34 (1.10–1.63)

Stomach

8

1.14 (0.49–2.25)

43

0.92 (0.66–1.24)

117

0.88 (0.72–1.05)

Colon/Rectum

29

1.17 (0.78–1.68)

200

1.03 (0.89–1.18)

385

0.83 (0.75–0.92)

Lung

13

1.31 (0.70–2.25)

83

1.13 (0.90–1.40)

90

0.93 (0.74–1.14)

Melanoma

54

1.18 (0.89–1.54)

88

0.89 (0.71–1.10)

98

0.88 (0.71–1.07)

Breast

70

0.79 (0.62–1.00)

227

0.89 (0.78–1.02)

283

0.77 (0.68–0.87)

Cervix

43

1.56 (1.13–2.11)

33

1.28 (0.88–1.80)

26

1.32 (0.86–1.93)

Endometrium

11

1.21 (0.60–2.16)

67

1.06 (0.82–1.35)

99

1.07 (0.87–1.31)

Ovary

15

1.72 (0.96–2.83)

26

1.09 (0.71–1.59)

31

0.93 (0.63–1.31)

Prostate

15

1.10 (0.62–1.81)

326

0.66 (0.59–0.74)

776

0.68 (0.63–0.73)

Bladder

15

1.65 (0.93–2.73)

126

1.41 (1.18–1.68)

220

1.07 (0.93–1.22)

Kidney

21

1.54 (0.96–2.36)

106

1.35 (1.10–1.63)

119

1.12 (0.93–1.34)

Thyroid gland

23

1.05 (0.66–1.57)

53

1.49 (1.12–1.95)

43

1.37 (0.99–1.84)

NHL high/low

10

1.24 (0.59–2.27)

45

1.29 (0.94–1.73)

56

1.15 (0.87–1.50)

CLL/ALL

3

1.86 (0.38–5.44)

14

0.71 (0.39–1.19)

39

1.11 (0.79–1.52)

All cancers combined

447

1.24 (1.12–1.36)

1784

1.02 (0.97–1.07)

2718

0.85 (0.82–0.89)

  1. Obs. Observed number of second primary cancers, SIR standardized incidence ratio, CI confidence interval, NHL non-Hodgkin Lymphoma, CLL chronic lymphatic leukaemia, ALL acute lymphatic leukaemia
  2. SIRs shown in normal bold fond indicate significantly increased risk; SIRs shown in bold italics indicate significantly decreased risk