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Table 4 SIR of second primary cancer by type of first primary cancer and age group at first diagnosis

From: The relative risk of second primary cancers in Austria’s western states: a retrospective cohort study

  Age group at first diagnosis
  15–49 years 50–64 years 65 years and over
First primary cancer Obs. SIR (95% CI) Obs. SIR (95% CI) Obs. SIR (95% CI)
Head/Neck/Larynx 42 2.35 (1.69–3.17) 189 2.21 (1.91–2.55) 103 1.34 (1.10–1.63)
Stomach 8 1.14 (0.49–2.25) 43 0.92 (0.66–1.24) 117 0.88 (0.72–1.05)
Colon/Rectum 29 1.17 (0.78–1.68) 200 1.03 (0.89–1.18) 385 0.83 (0.75–0.92)
Lung 13 1.31 (0.70–2.25) 83 1.13 (0.90–1.40) 90 0.93 (0.74–1.14)
Melanoma 54 1.18 (0.89–1.54) 88 0.89 (0.71–1.10) 98 0.88 (0.71–1.07)
Breast 70 0.79 (0.62–1.00) 227 0.89 (0.78–1.02) 283 0.77 (0.68–0.87)
Cervix 43 1.56 (1.13–2.11) 33 1.28 (0.88–1.80) 26 1.32 (0.86–1.93)
Endometrium 11 1.21 (0.60–2.16) 67 1.06 (0.82–1.35) 99 1.07 (0.87–1.31)
Ovary 15 1.72 (0.96–2.83) 26 1.09 (0.71–1.59) 31 0.93 (0.63–1.31)
Prostate 15 1.10 (0.62–1.81) 326 0.66 (0.59–0.74) 776 0.68 (0.63–0.73)
Bladder 15 1.65 (0.93–2.73) 126 1.41 (1.18–1.68) 220 1.07 (0.93–1.22)
Kidney 21 1.54 (0.96–2.36) 106 1.35 (1.10–1.63) 119 1.12 (0.93–1.34)
Thyroid gland 23 1.05 (0.66–1.57) 53 1.49 (1.12–1.95) 43 1.37 (0.99–1.84)
NHL high/low 10 1.24 (0.59–2.27) 45 1.29 (0.94–1.73) 56 1.15 (0.87–1.50)
CLL/ALL 3 1.86 (0.38–5.44) 14 0.71 (0.39–1.19) 39 1.11 (0.79–1.52)
All cancers combined 447 1.24 (1.12–1.36) 1784 1.02 (0.97–1.07) 2718 0.85 (0.82–0.89)
  1. Obs. Observed number of second primary cancers, SIR standardized incidence ratio, CI confidence interval, NHL non-Hodgkin Lymphoma, CLL chronic lymphatic leukaemia, ALL acute lymphatic leukaemia
  2. SIRs shown in normal bold fond indicate significantly increased risk; SIRs shown in bold italics indicate significantly decreased risk