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Table 1 Characteristics of cases and controls by factors matched (or surrogate factors) in the original study

From: The association between high birth weight and the risks of childhood CNS tumors and leukemia: an analysis of a US case-control study in an epidemiological database

Variables Controls Cases
CNS tumor Leukemia
(N = 822) (N = 72) (N = 124)
Year of birth 1946–1989 1952–1989 1949–1989
 1946–1959 120 (14.6%) 11 (15.3%) 22 (17.7%)
 1960–1969 240 (29.2%) 16 (22.2%) 44 (35.5%)
 1970–1979 294 (35.8%) 28 (38.9%) 35 (28.2%)
 1980–1989 168 (20.4%) 17 (23.6%) 23 (18.6%)
Age at diagnosis (years)a
 Mean (SD) 6.1 (4.4) 5.6 (4.3) 5.3 (4.1)
 Min-Max 0–15 0–14 0–14
Sex
 Male 493 (60.0%) 45 (62.5%) 71 (57.3%)
 Female 329 (40.0%) 27 (37.5%) 53 (42.7%)
Ethnicity
 Black 18 (2.2%) 3 (4.2%) 2 (1.6%)
 White 804 (97.8%) 69 (95.8%) 122 (98.4%)
Maternal age (years)
 Mean (SD) 25.5 (5.4) 25.2 (5.2) 25.5 (5.8)
 Min-Max 14–44 15–37 16–42
DOE sitesb
 Hanford 271 (32.9%) 19 (26.4%) 28 (22.6%)
 INEL 183 (22.3%) 15 (20.8%) 33 (26.6%)
 Oak Ridge 363 (44.2%) 37 (51.4%) 61 (49.2%)
 Unknown 5 (0.6%) 1 (1.4%) 2 (1.6%)
Gestational age (weeks)c
 Mean (SD) 39.3 (1.9) 38.5 (2.4) 39.4 (1.8)
 Min-Max 28–45 27–43 34–44
  1. SD standard deviation, DOE Department of Energy
  2. a Age at diagnosis for controls was calculated, using the year of diagnosis assigned by the original study, which was matched case-control study
  3. b DOE sites: a surrogate variable for county of residence
  4. c Not matched in the original study