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Fig. 3 | BMC Cancer

Fig. 3

From: A systematic investigation of the maximum tolerated dose of cytotoxic chemotherapy with and without supportive care in mice

Fig. 3

Effect of repeated cycles of chemotherapy given at MTD. Individual body weights as a percentage of starting weight for BALB/c mice (n = 3 per group) treated with repeated cycles of (a) vinorelbine 10 mg/kg, (b) cisplatin 6 mg/kg and (c) cisplatin 4 mg/kg. Doses were repeated when mice recovered to 100% of their starting weight. Arrows indicate dosing of respective chemotherapeutics. For vinorelbine this was day 0, 7, 14; for cisplatin 6 mg/kg this was day 0, 9; for cisplatin 4 mg/kg this was day 0, 8, 16

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