Table 7 Analysis of responsiveness of the FACIT-CD questionnaire

Physical well-being

No change

73

23.2

4.4

24.7

5.0

1.5

5.2

0.34

0.29

0.008

Improvement

83

22.9

4.3

25.5

3.2

2.5

4.0

0.58

0.63

< 0.001

Worsening

23

23.4

4.6

23.1

6.0

−0.3

4.5

−0.07

−0.07

0.87

Treatment satisfaction

No change

73

9.7

1.8

10.0

1.5

0.3

2.0

0.18

0.16

0.009

Improvement

83

9.5

1.8

10.2

1.5

0.7

1.9

0.43

0.38

< 0.001

Worsening

23

9.7

1.9

10.2

1.8

0.5

1.5

0.27

0.35

0.028

General perceptions

No change

73

18.5

4.0

16.6

3.8

−1.9

3.0

−0.48

−0.65

< 0.001

Improvement

83

18.5

3.7

17.4

2.8

−1.0

2.6

−0.29

−0.41

0.001

Worsening

23

19.1

2.7

18.3

2.5

−0.8

2.2

−0.29

−0.36

0.124

Emotional well-being

No change

73

30.3

6.6

33.3

5.2

3.0

5.5

0.45

0.54

< 0.001

Improvement

83

29.8

7.3

32.9

6.2

3.1

5.7

0.42

0.54

< 0.001

Worsening

23

32.0

5.3

34.0

4.7

1.9

5.3

0.36

0.36

0.038

Relationships

No change

73

8.6

2.1

8.8

2.2

0.2

1.9

0.009

0.10

0.021

Improvement

83

8.4

2.2

9.0

2.0

0.6

2.0

0.27

0.30

0.003

Worsening

23

9.0

2.1

9.1

2.9

0.1

2.1

0.06

0.06

0.284

FACIT-CD (total)

No change

73

90.4

11.2

93.6

11.7

3.1

10.7

0.27

0.29

0.003

Improvement

83

89.2

10.9

95.2

9.9

5.9

8.4

0.55

0.71

< 0.001

Worsening

23

93.4

10.3

94.9

11.3

1.4

9.7

0.14

0.15

0.429