Table 3 Crude and adjusted analyses association of genotype and environmental factors with stomach cancer
Variable | Cases (%) | Controls (%) | ORc (95% CI) | ORadj. (95% CI) | p-value |
|---|---|---|---|---|---|
n = 101 | n = 202 | ||||
XRCC1 gene | |||||
Gln/Gln | 48 (47.5) | 110 (54.5) | 1.0 | 1.0 | 0.041 |
Gln/Arg | 41 (40.6) | 84 (41.5) | 0.9 (0.59–1.55) | 1.2 (0.70–1.97) | |
Arg/Arg | 12 (11.9) | 8 (4.0) | 3.6 (1.32–9.60) | 3.7 (1.30–10.72) | |
Gender | 0.754 | ||||
Male | 57 (56.4) | 114 (56.4) | 1 | 1 | |
Female | 44 (43.6) | 88 (43.6) | 1.1 (0.83–1.49) | 1.5 (0.15–22.62) | |
Age (years) | 0.120 | ||||
< 60 | 70 (69.3) | 134 (66.3) | 1 | 1 | |
= > 60 | 31 (30.7) | 68 (33.7) | 0.5 (0.15–1.61) | 0.3 (0.15–1.58) | |
Family history of cancer | 0.013 | ||||
No | 61 (60.4) | 157 (77.7) | 1 | 1 | |
Yes | 40 (39.6) | 45 (22.3) | 2.3 (1.36–3.93) | 2.0 (1.37–4.00) | |
Gastritis history | 0.236 | ||||
No | 46 (45.5) | 111 (55.0) | 1 | 1 | |
Yes | 55 (54.5) | 91 (45.0) | 1.4 (0.89–2.31) | 1.3 (0.81–2.26) | |
Smoking | 0.399 | ||||
Nonsmoker | 49 (48.5) | 107 (53.0) | 1 | 1 | |
Smoker | 52 (51.5) | 95 (47.0) | 1.9 (0.76–5.01) | 1.6 (0.54–4.48) | |
Alcohol drinking | 0.140 | ||||
Nondrinker | 46 (45.5) | 110 (54.4) | 1 | 1 | |
Drinker | 55 (54.5) | 92 (45.6) | 1.8 (0.98–3.44) | 1.7 (0.84–3.21) | |
Vegetable oil intake | 0.028 | ||||
Low intake | 3 (3.0) | 17 (8.4) | 1 | 1 | |
High intake | 98 (97.0) | 185 (91.6) | 3.0 (1.85–10.33) | 3.2 (1.90–11.59) | |
Pork oil intake | 0.173 | ||||
Low intake | 89 (88.1) | 184 (91.1) | 1 | 1 | |
High intake | 12 (11.9) | 18 (8.9) | 1.4 (0.62–3.19) | 1.9 (0.74–5.13) | |
Salt intake | 0.124 | ||||
Low intake | 46 (45.5) | 72 (35.6) | 1 | 1 | |
High intake | 55 (54.5) | 130 (64.4) | 0.6 (0.37–1.05) | 0.7 (0.37–1.06) | |