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Table 2 Factors related to node metastasis in intermediate-risk EEC patients who underwent lymphadenectomy

From: Whether intermediate-risk stage 1A, grade 1/2, endometrioid endometrial cancer patients with lesions larger than 2 cm warrant lymph node dissection?

  Total(n = 624) Node metastasis (n = 12) p
Histologic subtype endometrioid 601 11 (1.8%) 0.372a
areas of squamous differentiation 23 1 (4.3%)
Tumor grade 1 504 8 (1.6%) 0.263a
2 120 4 (3.3%)
Histologic type of uninvolved endometrium simple hyperplasia 153 3 (2.0%) 0.636a
complex hyperplasia 5 0
secretory endometrium 19 0
complex hyperplasia with atypia 143 1(0.7%)
atrophic endometrium 121 2 (1.7%)
no uninvolved endometrium 183 6 (3.3%)
Myometrial invasion none 65 0 0.004a
superficial(<50%) 552 10 (1.8%)
superficial with MELF 7 2 (28.6%)
LVSI no 590 8 (1.4%) 0.004a
yes 34 4 (11.8%)
Lesion location fundus 198 2 (1.0%) 0.020a
cornua 87 3 (3.4%)
diffuse lesion 126 6(4.8%)
side wall & lower uterine segment 213 1(0.5%)
  1. Data anaylysis
  2. aFisher exact test