|
Measures
|
Total patients (N = 459)
|
Low (n = 104)
|
Mid (n = 130)
|
High (n = 225)
|
P
|
|---|
|
Lymph node metastasis (pN)
|
|
Negative
|
164 (35.7%)
|
66 (63.5%)
|
51 (39.2%)
|
47 (20.9%)
|
<0.001
|
|
Positive
|
295 (64.3%)
|
38 (36.5%)
|
79 (60.8%)
|
178 (79.1%)
| |
|
N1
|
98 (21.4%)
|
20 (19.2%)
|
30 (23.1%)
|
48 (21.3%)
| |
|
N2
|
99 (21.6%)
|
15 (14.4%)
|
26 (20.0%)
|
58 (25.8%)
| |
|
N3
|
98 (21.4%)
|
3 (2.9%)
|
23 (17.7%)
|
72 (32.0%)
| |
|
N3a
|
94 (20.5%)
|
3 (2.9%)
|
20 (15.4%)
|
71 (31.6%)
| |
|
N3b
|
4 (0.9%)
|
0 (0.0%)
|
3 (2.3%)
|
1 (0.4%)
| |
|
Number of metastatic lymph nodes
|
3.7 ± 4.9 (0–42)
|
1.2 ± 2.3 (0–12)
|
3.6 ± 5.8 (0–42)
|
4.9 ± 4.7 (0–25)
|
<0.001
|
|
Number of retrieved lymph nodes
|
42.4 ± 15.4 (6–106)
|
39.5 ± 13.3 (14–78)
|
44.9 ± 16.1* (8–97)
|
42.4 ± 15.8 (6–106)
|
0.028
|
|
Positive lymph node ratio
|
0.09 ± 0.12
|
0.03 ± 0.06
|
0.08 ± 0.12
|
0.12 ± 0.13
|
<0.001
|
|
Lymphatic invasiona
|
|
Negative
|
154 (33.6%)
|
59 (57.3%)
|
45 (34.9%)
|
50 (22.2%)
|
<0.001
|
|
Positive
|
303 (66.0%)
|
44 (42.7%)
|
84 (65.1%)
|
175 (77.8%)
| |
-
*
p < 0.05; when compared with “low Slug composite score group” using the ANOVA test with post-hoc Tukey-HSD test
-
aLymphatic invasion could not be evaluated in 2 cases
