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Table 3 Association of lymphatic metastasis and Slug expression

From: Evaluation of Slug expression is useful for predicting lymph node metastasis and survival in patients with gastric cancer

Measures Total patients (N = 459) Low (n = 104) Mid (n = 130) High (n = 225) P
Lymph node metastasis (pN)
 Negative 164 (35.7%) 66 (63.5%) 51 (39.2%) 47 (20.9%) <0.001
 Positive 295 (64.3%) 38 (36.5%) 79 (60.8%) 178 (79.1%)  
  N1 98 (21.4%) 20 (19.2%) 30 (23.1%) 48 (21.3%)  
  N2 99 (21.6%) 15 (14.4%) 26 (20.0%) 58 (25.8%)  
  N3 98 (21.4%) 3 (2.9%) 23 (17.7%) 72 (32.0%)  
   N3a 94 (20.5%) 3 (2.9%) 20 (15.4%) 71 (31.6%)  
   N3b 4 (0.9%) 0 (0.0%) 3 (2.3%) 1 (0.4%)  
Number of metastatic lymph nodes 3.7 ± 4.9 (0–42) 1.2 ± 2.3 (0–12) 3.6 ± 5.8 (0–42) 4.9 ± 4.7 (0–25) <0.001
Number of retrieved lymph nodes 42.4 ± 15.4 (6–106) 39.5 ± 13.3 (14–78) 44.9 ± 16.1* (8–97) 42.4 ± 15.8 (6–106) 0.028
Positive lymph node ratio 0.09 ± 0.12 0.03 ± 0.06 0.08 ± 0.12 0.12 ± 0.13 <0.001
Lymphatic invasiona
 Negative 154 (33.6%) 59 (57.3%) 45 (34.9%) 50 (22.2%) <0.001
 Positive 303 (66.0%) 44 (42.7%) 84 (65.1%) 175 (77.8%)  
  1. * p < 0.05; when compared with “low Slug composite score group” using the ANOVA test with post-hoc Tukey-HSD test
  2. aLymphatic invasion could not be evaluated in 2 cases