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Table 2 Comparison of characteristics of the patients according to Slug composite score

From: Evaluation of Slug expression is useful for predicting lymph node metastasis and survival in patients with gastric cancer

Measures Total patients (N = 459) Low (n = 104) Mid (n = 130) High (n = 225) P
Age (years)
 Mean ± SD 58.6 ± 11.9 56.3 ± 12.3 58.9 ± 11.8 59.6 ± 11.6 0.064
 Range 23–86 23–81 32–82 24–86  
Male 313 (68.2%) 65 (62.5%) 94 (72.3%) 154 (68.4%) 0.276
Type of surgery
 Total gastrectomy 166 (36.2%) 30 (28.8%) 51 (39.2%) 85 (37.8%)  
 Subtotal gastrectomy 290 (63.2%) 73 (70.2%) 78 (60.0%) 139 (61.8%)  
 Wedge resection 3 (0.7%) 1 (1.0%) 1 (0.8%) 1 (0.4%)  
Tumor size (cm)
 Mean ± SD 5.0 ± 2.9 4.1 ± 2.5 5.1 ± 3.3 5.4 ± 2.8 0.001
 Range 0.2–19.0 0.4–12.5 0.5–19.0 0.2–15.5  
Location
 Upper third 80 (17.4%) 16 (15.4%) 22 (16.9%) 42 (18.7%) 0.599
 Middle third 164 (35.7%) 43 (41.3%) 50 (38.5%) 71 (31.6%)  
 Lower third 206 (44.9%) 44 (42.3%) 55 (42.3%) 107 (47.6%)  
 Whole stomach 9 (2.0%) 1 (1.0%) 3 (2.3%) 5 (2.2%)  
Tumor depth (pT)
 T1 120 (26.1%) 56 (53.8%) 30 (23.1%) 34 (15.1%) <0.001
 T2 62 (13.5%) 18 (17.3%) 26 (20.0%) 18 (8.0%)  
 T3 121 (26.4%) 14 (13.5%) 35 (26.9%) 72 (32.0%)  
 T4 156 (34.0%) 16 (15.4%) 39 (30.0%) 101 (44.9%)  
TNM Stage
 I 131 (28.5%) 62 (59.6%) 37 (28.5%) 32 (14.2%) <0.001
 II 122 (26.6%) 25 (24.0%) 45 (34.6%) 52 (23.1%)  
 III 206 (44.9%) 17 (16.3%) 48 (36.9%) 141 (62.7%)  
Venous invasiona
 Negative 406 (88.5%) 97 (94.2%) 117 (90.0%) 192 (85.3%) 0.055
 Positive 52 (11.3%) 6 (5.8%) 13 (10.0%) 33 (14.7%)  
Perineural invasion
 Negative 270 (58.8%) 81 (77.9%) 75 (57.7%) 114 (50.7%) <0.001
 Positive 189 (41.2%) 23 (22.1%) 55 (42.3%) 111 (49.3%)  
Histology
 Adenocarcinoma      0.005b
  Well differentiated 38 (8.3%) 12 (11.5%) 5 (3.8%) 21 (9.3%)  
  Moderately differentiated 136 (29.6%) 23 (22.1%) 44 (33.8%) 69 (30.7%)  
  Poorly differentiated 189 (41.2%) 35 (33.7%) 53 (40.8%) 101 (44.9%)  
 Mucinous adenocarcinoma 19 (4.1%) 5 (4.8%) 7 (5.4%) 7 (3.1%)  
 Signet ring cell carcinoma 77 (16.8%) 29 (27.9%) 21 (16.2%) 27 (12.0%)  
Lauren classification
 Intestinal 174 (37.9%) 40 (38.5%) 47 (36.2%) 87 (38.7%) 0.433
 Diffuse 177 (38.6%) 40 (38.5%) 58 (44.6%) 79 (35.1%)  
 Mixed 108 (23.5%) 24 (23.1%) 25 (19.2%) 59 (26.2%)  
  1. Where appropriate, data are shown as the mean ± SD
  2. aLymphatic and venous invasion could not be evaluated in 2 and 1 cases, respectively
  3. bLinear-by-linear association