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Table 2 Comparison of characteristics of the patients according to Slug composite score

From: Evaluation of Slug expression is useful for predicting lymph node metastasis and survival in patients with gastric cancer

Measures

Total patients (N = 459)

Low (n = 104)

Mid (n = 130)

High (n = 225)

P

Age (years)

 Mean ± SD

58.6 ± 11.9

56.3 ± 12.3

58.9 ± 11.8

59.6 ± 11.6

0.064

 Range

23–86

23–81

32–82

24–86

 

Male

313 (68.2%)

65 (62.5%)

94 (72.3%)

154 (68.4%)

0.276

Type of surgery

 Total gastrectomy

166 (36.2%)

30 (28.8%)

51 (39.2%)

85 (37.8%)

 

 Subtotal gastrectomy

290 (63.2%)

73 (70.2%)

78 (60.0%)

139 (61.8%)

 

 Wedge resection

3 (0.7%)

1 (1.0%)

1 (0.8%)

1 (0.4%)

 

Tumor size (cm)

 Mean ± SD

5.0 ± 2.9

4.1 ± 2.5

5.1 ± 3.3

5.4 ± 2.8

0.001

 Range

0.2–19.0

0.4–12.5

0.5–19.0

0.2–15.5

 

Location

 Upper third

80 (17.4%)

16 (15.4%)

22 (16.9%)

42 (18.7%)

0.599

 Middle third

164 (35.7%)

43 (41.3%)

50 (38.5%)

71 (31.6%)

 

 Lower third

206 (44.9%)

44 (42.3%)

55 (42.3%)

107 (47.6%)

 

 Whole stomach

9 (2.0%)

1 (1.0%)

3 (2.3%)

5 (2.2%)

 

Tumor depth (pT)

 T1

120 (26.1%)

56 (53.8%)

30 (23.1%)

34 (15.1%)

<0.001

 T2

62 (13.5%)

18 (17.3%)

26 (20.0%)

18 (8.0%)

 

 T3

121 (26.4%)

14 (13.5%)

35 (26.9%)

72 (32.0%)

 

 T4

156 (34.0%)

16 (15.4%)

39 (30.0%)

101 (44.9%)

 

TNM Stage

 I

131 (28.5%)

62 (59.6%)

37 (28.5%)

32 (14.2%)

<0.001

 II

122 (26.6%)

25 (24.0%)

45 (34.6%)

52 (23.1%)

 

 III

206 (44.9%)

17 (16.3%)

48 (36.9%)

141 (62.7%)

 

Venous invasiona

 Negative

406 (88.5%)

97 (94.2%)

117 (90.0%)

192 (85.3%)

0.055

 Positive

52 (11.3%)

6 (5.8%)

13 (10.0%)

33 (14.7%)

 

Perineural invasion

 Negative

270 (58.8%)

81 (77.9%)

75 (57.7%)

114 (50.7%)

<0.001

 Positive

189 (41.2%)

23 (22.1%)

55 (42.3%)

111 (49.3%)

 

Histology

 Adenocarcinoma

    

0.005b

  Well differentiated

38 (8.3%)

12 (11.5%)

5 (3.8%)

21 (9.3%)

 

  Moderately differentiated

136 (29.6%)

23 (22.1%)

44 (33.8%)

69 (30.7%)

 

  Poorly differentiated

189 (41.2%)

35 (33.7%)

53 (40.8%)

101 (44.9%)

 

 Mucinous adenocarcinoma

19 (4.1%)

5 (4.8%)

7 (5.4%)

7 (3.1%)

 

 Signet ring cell carcinoma

77 (16.8%)

29 (27.9%)

21 (16.2%)

27 (12.0%)

 

Lauren classification

 Intestinal

174 (37.9%)

40 (38.5%)

47 (36.2%)

87 (38.7%)

0.433

 Diffuse

177 (38.6%)

40 (38.5%)

58 (44.6%)

79 (35.1%)

 

 Mixed

108 (23.5%)

24 (23.1%)

25 (19.2%)

59 (26.2%)

 
  1. Where appropriate, data are shown as the mean ± SD
  2. aLymphatic and venous invasion could not be evaluated in 2 and 1 cases, respectively
  3. bLinear-by-linear association