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Fig. 3 | BMC Cancer

Fig. 3

From: Cancer associated fibroblasts (CAFs) are activated in cutaneous basal cell carcinoma and in the peritumoural skin

Fig. 3

Gene expression of cytokine and chemokine mRNA by qRT-PCR. The mRNA expression levels of the cytokines CCL17, CCL18, CCL22, CCL25, and CXCL12 in BCC and peritumoural skin reveals increased expression in BCC and peritumoral skin whereas there is no expression in the normal non UV-exposed buttock skin. BCC tumour (T), n = 18 for all markers except CCL25 n = 17); peritumoural skin (P), n = 18 for all markers, and buttock (B), n = 18 (CXCL12), n = 16 (CCL17), n = 14 (CCL18), n = 12 (CCL22), n = 11 (CCL25). Significance level * = p < 0.5, ** = p < 0.001, *** = p < 0.0001. Where no *, no statiscally significant difference detected

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