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Fig. 1 | BMC Cancer

Fig. 1

From: Lysosome trafficking is necessary for EGF-driven invasion and is regulated by p38 MAPK and Na+/H+ exchangers

Fig. 1

HGF and EGF mediate cell scattering via different downstream signaling pathways. a DU145 cells were pretreated with 10 μM of the indicated inhibitors or 0.1% DMSO for 30 min prior to stimulation with 100 ng/mL EGF or 33 ng/mL HGF for 16 h. Cells were fixed and stained with phalloidin. Cell scattering was imaged in 10X fields, N = 3. b Represents % scattered cells analyzed from three independent experiments. * = p < 0.001 compared to EGF control and ** = p < 0.001 compared to HGF control

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