Benefits of home-based multidisciplinary exercise and supportive care in inoperable non-small cell lung cancer – protocol for a phase II randomised controlled trial

Table 2 Summary of outcome measures

	Time point
Outcomes	Baseline	Post-program (9-weeks)	4-months (telephone)	6-months
Primary outcome
6MWD	✓	✓		✓
Key secondary outcomes
Physical Activity
Accelerometry	✓	✓		✓
IPAQ	✓	✓		✓
Strength
HHD quadriceps	✓	✓		✓
HGD	✓	✓		✓
Secondary outcomes
HRQoL
FACT-L	✓	✓		✓
AQoL	✓	✓		✓
PAAI	✓	✓		✓
BREQ-2	✓	✓		✓
MDASI-LC	✓	✓		✓
HADS	✓	✓		✓
CD-RISC	✓	✓		✓
Health economic questionnaire		✓	✓	✓
Qualitative interviews (subset)		✓
Exploratory outcomes (subset)
Venous blood sample	✓	✓
Quadriceps size and echogenicity	✓	✓

6MWD six minute walk distance, IPAQ International Physical Activity Questionnaire, HHD hand-held dynamometry, HGD handgrip dynamometry, HRQoL health-related quality of life, FACT-L Functional Assessment of Cancer Therapy-Lung, AQoL Assessment of Quality of Life, PAAI Physical Activity Assessment Inventory, BREQ-2 Behavioural Regulation in Exercise Questionnaire Version 2, MDASI-LC MD Anderson Symptom Inventory-Lung Cancer, HADS Hospital Anxiety and Depression Scale, CD-RISC Connor Davidson Resilience Scale. Survival, collected until 3-years, and serious and minor adverse events will be collected until 6-months

ISSN: 1471-2407