Table 3 uPA/PAI-1 and Ki67 levels stratified according to tumour grade
From: Assessment of Ki67 and uPA/PAI-1 expression in intermediate-risk early stage breast cancers
GRADE I | ||||||
Positive | Negative | Positive vs. negative uPA/PAI-1 | ||||
Ki67 | uPA+/PAI-1+ | uPA +/PAI-1- | uPA−/PAI-1+ | uPA−/PAI-1- | Total | P value |
< 20% | 11 (16) | 4 (6) | 22 (31) | 34 (47) | 71 | 0.5 |
≥ 20% | 1 (33) | 0 (0) | 0 (0) | 2 (67) | 3 | |
GRADE II | ||||||
Positive | Negative | Positive vs. negative uPA/PAI-1 | ||||
Ki67 | uPA+/PAI-1+ | uPA+/PAI-1- | uPA−/PAI-1+ | uPA−/PAI-1- | Total | P value |
< 20% | 42 (25) | 15 (9) | 43 (25) | 70 (41) | 170 | 0.04 |
≥ 20% | 24 (42) | 6 (10) | 12 (21) | 15 (27) | 57 | |
GRADE III | ||||||
Positive | Negative | Positive vs. negative uPA/PAI-1 | ||||
Ki67 | uPA+/PAI-1+ | uPA+/PAI-1- | uPA−/PAI-1+ | uPA−/PAI-1- | Total | P value |
< 20% | 3 (33) | 4 (45) | 1 (11) | 1 (11) | 9 | 0.1 |
≥ 20% | 11 (30) | 6 (16) | 7 (19) | 13 (35) | 37 | |