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Table 3 Standardized incidence ratios (SIR) and 95% confidence intervals (CI) for risk of second primary prostate cancer and absolute excess risk per 10,000 person-years among male breast cancer cases from the SEER 18 registries, 1988–2012

From: Descriptive characteristics of prostate cancer in patients with a history of primary male breast cancer – a SEER analysis

  SIR (95% CI) Excess risk per 10,000 Mean person-years at risk
Overall 1.12 (0.93–1.33) 7.65 6.05
Stratified estimates
Age at index breast cancer, years
 20–55 1.22 (0.68–2.01) 5.94 7.41
 55–64 1.20 (0.87–1.62) 14.77 6.64
 65–74 1.34 (1.01–1.73) 30.28 6.17
 75+ 0.54 (0.29–0.93) −34.17 4.28
Race/ethnicity
 Non-Hispanic White 1.12 (0.91–1.37) 8.33 6.23
 Black 1.14 (0.68–1.81) 12.28 5.07
 Asian/Pacific Islander/Alaska Native 1.16 (0.38–2.70) 5.88 6.35
 Hispanic 1.01 (0.33–2.35) 0.32 5.31
Breast cancer AJCC stage     
 I 1.36 (1.04–1.75) 23.70 7.25
 II 1.17 (0.87–1.54) 11.18 6.04
 III 0.71 (0.36–1.28) −19.29 4.83
Hormone receptor status     
 ER/PR negative 0.26 (0.01–1.44)a −47.13 6.04
 ER and/or PR positive 1.23 (1.11–1.39) 22.11 7.27
  1. aEstimate based on <5 observed cases