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Table 4 Metastasis-associated genes that displayed significant changes in expression after Rep stress (but not Acu)

From: Stress alters the expression of cancer-related genes in the prostate

Gene ID/ Accession

Gene name

Fold change

Con vs Rep

Molecular function/biological process

Ccl7 Q9QXY8

Chemokine (C-C motif) ligand 7

11.00

Cytokine/immune function (chemotaxis)

Il1b Q63264

Interleukin 1 beta

3.84

Cytokine/immune function (inflammation)

Plaur P49616

Plasminogen activator, urokinase receptor

6.63

Transmembrane protein/differentiation

Src Q9WUD9

V-src sarcoma

1.93

Non-receptor tyrosine kinase/proliferation

Tp53* P10361

Tumor protein p53

0.50

Transcription factor/DNA repair, apoptosis

  1. Italicized text denotes genes that remained significantly changed after recovery. Only one gene was found to have downregulated expression (asterisk); bold text denotes genes identified as proto-oncogenes; bold and italicized text denotes tumor suppressor genes. Accession numbers and molecular function/biological process obtained from UniProtKB database
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BMC Cancer

ISSN: 1471-2407

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