Table 1 Cancer pathway genes with significant upregulation after Acu and Rep stress, returning to normal after recovery
From: Stress alters the expression of cancer-related genes in the prostate
Gene ID/ Accesion | Gene name | Fold change Con vs Acu | Fold change Con vs Rep | Molecular function/biological process |
|---|---|---|---|---|
Arnt P41739 | Aryl hydrocarbon receptor nuclear translocator | 1.51 | 1.23 (ns) | Transcription factor/response to hypoxia |
Ets2 D4AAH4 | V-ets erythroblastosis virus E26 oncogene homolog 2 (avian) | 1.83 | 1.93 | Transcription factor/cell differentiation |
Krt14 Q6IFV1 | Keratin 14 | 2.27 | 2.27 | Cytoskeleton/maintenance of cell morphology |
Serpinb2 P29524 | Serpin peptidase inhibitor, clade B (ovalbumin), member 2 | 1.97 | 1.99 | Endopeptidase inhibitor/apoptosis |
Skp2 B2GUZ0 | S-phase kinase-associated protein 2 (p45) | 1.56 | 1.67 | Ubiquitin ligase/cell cycle regulation |
Slc2a1 P11167 | Solute carrier family 2 (facilitated glucose transporter, member 1 | 1.25 | 1.32 | Glucose transporter/metabolism (nutrient uptake) |
Tinf2 Q5XIB8 | TERF 1 (TRF1)- interacting nuclear factor 2 | 4.29 | 6.11 | Telomeric DNA binding/chrosomome stability |