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Table 1 Cancer pathway genes with significant upregulation after Acu and Rep stress, returning to normal after recovery

From: Stress alters the expression of cancer-related genes in the prostate

Gene ID/ Accesion Gene name Fold change
Con vs Acu
Fold change
Con vs Rep
Molecular function/biological process
Arnt P41739 Aryl hydrocarbon receptor nuclear translocator 1.51 1.23 (ns) Transcription factor/response to hypoxia
Ets2 D4AAH4 V-ets erythroblastosis virus E26 oncogene homolog 2 (avian) 1.83 1.93 Transcription factor/cell differentiation
Krt14 Q6IFV1 Keratin 14 2.27 2.27 Cytoskeleton/maintenance of cell morphology
Serpinb2 P29524 Serpin peptidase inhibitor, clade B (ovalbumin), member 2 1.97 1.99 Endopeptidase inhibitor/apoptosis
Skp2 B2GUZ0 S-phase kinase-associated protein 2 (p45) 1.56 1.67 Ubiquitin ligase/cell cycle regulation
Slc2a1 P11167 Solute carrier family 2 (facilitated glucose transporter, member 1 1.25 1.32 Glucose transporter/metabolism (nutrient uptake)
Tinf2 Q5XIB8 TERF 1 (TRF1)- interacting nuclear factor 2 4.29 6.11 Telomeric DNA binding/chrosomome stability
  1. Italicized text denotes a gene that was only upregulated with Acu (but not Rep) stress, as indicated by “ns”; bold text denotes genes identified as proto-oncogenes. Accession numbers and molecular function/biological process obtained from UniProtKB database