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Table 3 Assessment for heterogeneity using a percent positive binarization cut-point of >10

From: Programmed cell death ligand 1 cut-point is associated with reduced disease specific survival in resected pancreatic ductal adenocarcinoma

Variable Levels PD-L1%Positive < 10 PD-L1%Positive > 10 P-Value
Age Median [IQR] 66.5 [13.1] 65.6 [20.5] 0.96
Sex Male 132 (55.0%) 7 (58.3%) 1.0
Female 108 (45.0%) 4 (41.8%)
Adjuvant Chemotherapy Given 71 (29.6%) 3 (25.0%) 1.0
Observation 169 (70.4%) 9 (75.0%)
Histologic Grade 1 2 (0.8%) 0 (0.0%) 0.029
2 181 (75.4%) 5 (41.7%)
3 57 (23.8%) 7 (58.3%)
Lymphovascular Invasion Present 136 (56.7%) 8 (66.7%) 0.56
Absent 104 (43.3%) 4 (33.3%)
Perineurial Invasion Present 221 (92.1%) 11 (91.7%) 1.0
Absent 19 (7.9%) 1 (9.3%)
pT Stage 1 2 (0.8%) 0 (0.0%) 0.88
2 10 (4.2%) 1 (8.3%)
3 227 (94.6%) 11 (91.7%)
4 1 (0.4%) 0 (0.0%)
pN Stage 0 62 (25.8%) 2 (16.7%) 0.74
1 178 (74.2%) 10 (83.3%)
Resection Status R0 184 (76.7%) 6 (50%) 0.08
R1 56 (23.3%) 6 (50%)
CD3 Epithelial Median [IQR] 0 [0] 0 [4] 0.16
CD3 Stromal Median [IQR] 50 [52] 63 [76] 0.52
CD8 Epithelial Median [IQR] 0 [0] 0 [0] 0.51
CD8 Stromal Median [IQR] 11 [36] 14 [39] 0.72
MMR Status Proficient 200 (83.7%) 11 (91.7%) 0.70
Deficient 39 (16.3%) 1 (8.3%)