Skip to main content

Table 2 Percentage of cases with hypermethylation

From: BRCA2 carriers with male breast cancer show elevated tumour methylation

  GSTP1 RASSF1A MAL TWIST RUNX3 RARβ APC FOXC1 CDH1 WIF1 TOTAL HYPERMETHYLATED GENES AMI (mean)
BRCA1 (n = 3) 2 (66%) 1 (33%) 1 (33%) 0 1 (33%) 1 (33%) 1 (33%) 1 (33%) 0 1 (33%) 9 (30%) 13.4
BRCA2 (n = 25) 22 (88%) 20 (80%) 14 (56%) 13 (52%) 8 (32%) 11 (44%) 8 (32%) 6 (24%) 0 11 (44%) 113 (45%) 23.6
BRCAX (n = 32) 25 (78%) 20 (63%) 12 (38%) 9 (28%) 9 (28%) 6 (19%) 7 (22%) 8 (25%) 0 14 (56%) 110 (34%) 17.0
All (n = 60) 49 (82%) 41 (68%) 27 (45%) 22 (37%) 18 (30%) 18 (30%) 16 (27%) 15 (25%) 0 26 (43%) 232 (39%) 14.0
     p = 0.06   p = 0.08      P < 0.01 p = 0.01