Table 3 Clinical and pathological characteristics of the CHEK2 c.1100delC carriers
Age range at diagnosis | T | N | M | Histology | ER | PR | Grade | Her2 | Family history of breast cancer | Family history of prostate cancer | Family history of ovarian cancer | BRCA1/2 mutation |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
65–70 | 1 | 1 | 0 | Ductal | Positive | Positive | 3 | n.a. | n.a. | n.a. | n.a. | Negative |
45–50 | 1 | 0 | 0 | Ductal | Positive | Negative | 2 | n.a. | Negative | Negative | Negative | Negative |
40–45 | 1 | 1 | 0 | Ductal | Positive | Negative | 3 | Negative | Positive | n.a. | n.a. | Negative |
75–80 | 1 | 0 | 0 | Ductal | Positive | Positive | 2 | Positive | Negative | n.a. | n.a. | Negative |