CHEK2 c.1100delC mutation is associated with an increased risk for male breast cancer in Finnish patient population

Table 2 The frequencies of mutations detected in study and control populations

Mutation	This study	Freq^a	Controls^b	Freq^c	p-value	OR	95% CI	Ref
CHEK2 c.1100delC	4 of 68	0.059	26 of 1885	0.014	0.019	4.47	1.51–13.18	8
CHEK2 I157T	4 of 68	0.059	100 of 1885	0.053	0.781	1.12	0.40–3.13	12
PALB2 c.1592delT	0 of 68	0	2 of 1079	0.002	1	n.a.	n.a.	22
FANCM p.Q1701X	0 of 68	0	38 of 2080	0.018	0.632	n.a.	n.a.	25
RAD51C c.93delG	0 of 68	0	2 of 2086	0.001	1	n.a.	n.a.	18
RAD51C c.837+1G>A	0 of 68	0	0 of 2086	0	1	n.a.	n.a.	18
RAD51D c.576+1G>A	0 of 68	0	1 of 2102	0	1	n.a.	n.a.	24

ISSN: 1471-2407