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Table 2 The frequencies of mutations detected in study and control populations

From: CHEK2 c.1100delC mutation is associated with an increased risk for male breast cancer in Finnish patient population

Mutation This study Freqa Controlsb Freqc p-value OR 95% CI Ref
CHEK2 c.1100delC 4 of 68 0.059 26 of 1885 0.014 0.019 4.47 1.51–13.18 8
CHEK2 I157T 4 of 68 0.059 100 of 1885 0.053 0.781 1.12 0.40–3.13 12
PALB2 c.1592delT 0 of 68 0 2 of 1079 0.002 1 n.a. n.a. 22
FANCM p.Q1701X 0 of 68 0 38 of 2080 0.018 0.632 n.a. n.a. 25
RAD51C c.93delG 0 of 68 0 2 of 2086 0.001 1 n.a. n.a. 18
RAD51C c.837+1G>A 0 of 68 0 0 of 2086 0 1 n.a. n.a. 18
RAD51D c.576+1G>A 0 of 68 0 1 of 2102 0 1 n.a. n.a. 24
  1. amutation frequency in this study
  2. bsee cited reference for control populations
  3. cmutation frequency in controls