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Table 3 Multivariate analysis of prognostic factors based on Cox proportional hazards regression model in 136 primary PCa patients progressing to metastatic hormone-sensitive disease after curative treatment

From: The outcome of prostate cancer patients treated with curative intent strongly depends on survival after metastatic progression

Variable Hazard ratio 95% CI p-value
Age at diagnosis (years) 1.05 0.97–1.13 0.213
PSA (ng/ml)
 10–20 vs < 10 0.31 0.09–1.13 0.076
  > 20 vs < 10 1.47 0.66–3.29 0.348
Stage
 T3-T4 vs T1-T2 0.82 0.31–2.38 0.687
Gleason Score
  > 7 vs ≤ 7 2.47 1.15–5.29 0.020*
Site of metastasis at first progression
 Bone-only vs Loco/LN-only 3.88 1.37–10.98 0.011*
 Visceral-only vs Loco/LN-only 1.89 0.20–18.10 0.582
 Multiple site vs Loco/LN-only 3.56 1.24–10.24 0.019*
  1. CI Confidence interval; * significant value